Cytokines as Biomarkers in Rheumatoid Arthritis
Joint Authors
Ponchel, Frédérique
Burska, Agata N.
Boissinot, Marjorie
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-09
Country of Publication
Egypt
No. of Pages
24
Main Subjects
Abstract EN
RA is a complex disease that develops as a series of events often referred to as disease continuum.
RA would benefit from novel biomarker development for diagnosis where new biomarkers are still needed (even if progresses have been made with the inclusion of ACPA into the ACR/EULAR 2010 diagnostic criteria) and for prognostic notably in at risk of evolution patients with autoantibody-positive arthralgia.
Risk biomarkers for rapid evolution or cardiovascular complications are also highly desirable.
Monitoring biomarkers would be useful in predicting relapse.
Finally, predictive biomarkers for therapy outcome would allow tailoring therapy to the individual.
Increasing numbers of cytokines have been involved in RA pathology.
Many have the potential as biomarkers in RA especially as their clinical utility is already established in other diseases and could be easily transferable to rheumatology.
We will review the current knowledge’s relation to cytokine used as biomarker in RA.
However, given the complexity and heterogeneous nature of RA, it is unlikely that a single cytokine may provide sufficient discrimination; therefore multiple biomarker signatures may represent more realistic approach for the future of personalised medicine in RA.
American Psychological Association (APA)
Burska, Agata N.& Boissinot, Marjorie& Ponchel, Frédérique. 2014. Cytokines as Biomarkers in Rheumatoid Arthritis. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-24.
https://search.emarefa.net/detail/BIM-1043636
Modern Language Association (MLA)
Burska, Agata N.…[et al.]. Cytokines as Biomarkers in Rheumatoid Arthritis. Mediators of Inflammation No. 2014 (2014), pp.1-24.
https://search.emarefa.net/detail/BIM-1043636
American Medical Association (AMA)
Burska, Agata N.& Boissinot, Marjorie& Ponchel, Frédérique. Cytokines as Biomarkers in Rheumatoid Arthritis. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-24.
https://search.emarefa.net/detail/BIM-1043636
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043636