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Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract
Joint Authors
Wasniewski, Tomasz
Rawińska, Paulina
Sinderewicz, Emilia
Kowalczyk-Zieba, Ilona
Wocławek-Potocka, Izabela
Boruszewska, Dorota
Skarzynski, Dariusz J.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-12
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Lysophosphatidic acid (LPA) through activating its G protein-coupled receptors (LPAR 1–6) exerts diverse cellular effects that in turn influence several physiological processes including reproductive function of the female.
Studies in various species of animals and also in humans have identified important roles for the receptor-mediated LPA signaling in multiple aspects of human and animal reproductive tract function.
These aspects range from ovarian and uterine function, estrous cycle regulation, early embryo development, embryo implantation, decidualization to pregnancy maintenance and parturition.
LPA signaling can also have pathological consequences, influencing aspects of endometriosis and reproductive tissue associated tumors.
The review describes recent progress in LPA signaling research relevant to human and ruminant reproduction, pointing at the cow as a relevant model to study LPA influence on the human reproductive performance.
American Psychological Association (APA)
Wocławek-Potocka, Izabela& Rawińska, Paulina& Kowalczyk-Zieba, Ilona& Boruszewska, Dorota& Sinderewicz, Emilia& Wasniewski, Tomasz…[et al.]. 2014. Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1043700
Modern Language Association (MLA)
Wocławek-Potocka, Izabela…[et al.]. Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract. Mediators of Inflammation No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1043700
American Medical Association (AMA)
Wocławek-Potocka, Izabela& Rawińska, Paulina& Kowalczyk-Zieba, Ilona& Boruszewska, Dorota& Sinderewicz, Emilia& Wasniewski, Tomasz…[et al.]. Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1043700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043700