A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production
Joint Authors
Prates, E. G.
Nunes, J. T.
Pereira, R. M.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Oocyte intracellular lipids are mainly stored in lipid droplets (LD) providing energy for proper growth and development.
Lipids are also important signalling molecules involved in the regulatory mechanisms of maturation and hence in oocyte competence acquisition.
Recent studies show that LD are highly dynamic organelles.
They change their shape, volume, and location within the ooplasm as well as their interaction with other organelles during the maturation process.
The droplets high lipid content has been correlated with impaired oocyte developmental competence and low cryosurvival.
Yet the underlying mechanisms are not fully understood.
In particular, the lipid-rich pig oocyte might be an excellent model to understand the role of lipids and fatty acid metabolism during the mammalian oocyte maturation and their implications on subsequent monospermic fertilization and preimplantation embryo development.
The possibility of using chemical molecules to modulate the lipid content of oocytes and embryos to improve cryopreservation as well as its biological effects during development is here described.
Furthermore, these principles of lipid content modulation may be applied not only to germ cells and embryo cryopreservation in livestock production but also to biomedical fundamental research.
American Psychological Association (APA)
Prates, E. G.& Nunes, J. T.& Pereira, R. M.. 2014. A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043724
Modern Language Association (MLA)
Prates, E. G.…[et al.]. A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production. Mediators of Inflammation No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1043724
American Medical Association (AMA)
Prates, E. G.& Nunes, J. T.& Pereira, R. M.. A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043724
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043724