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Excessive Refined Carbohydrates and Scarce Micronutrients Intakes Increase Inflammatory Mediators and Insulin Resistance in Prepubertal and Pubertal Obese Children Independently of Obesity
Joint Authors
López-Alarcón, Mardia
Flores-Huerta, Samuel
Inda-Icaza, Patricia
Rodríguez-Cruz, Maricela
Armenta-Álvarez, Andrea
Bram-Falcón, María Teresa
Mayorga-Ochoa, Marielle
Perichart-Perera, Otilia
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Low-grade inflammation is the link between obesity and insulin resistance.
Because physiologic insulin resistance occurs at puberty, obese pubertal children are at higher risk for insulin resistance.
Excessive diets in refined carbohydrates and saturated fats are risk factors for insulin resistance, but calcium, magnesium, vitamin-D, and the omega-3 fatty acids likely protect against inflammation and insulin resistance.
Objective.
To analyze interactions among dietary saturated fat, refined carbohydrates, calcium, magnesium, vitamin D, and omega-3 fatty acids on the risk of inflammation and insulin resistance in a sample of prepubertal and pubertal children.
Methods.
A sample of 229 children from Mexico City was analyzed in a cross-sectional design.
Anthropometric measurements, 24 h recall questionnaires, and blood samples were obtained.
Serum insulin, glucose, calcium, magnesium, 25-OHD3, C-reactive protein, leptin, adiponectin, and erythrocytes fatty acids were measured.
Parametric and nonparametric statistics were used for analysis.
Results.
While mean macronutrients intake was excessive, micronutrients intake was deficient (P<0.01).
Inflammation determinants were central obesity and magnesium-deficient diets.
Determinants of insulin resistance were carbohydrates intake and circulating magnesium and adiponectin.
Conclusions.
Magnesium-deficient diets are determinants of inflammation, while high intake of refined carbohydrates is a risk factor for insulin resistance, independently of central adiposity.
American Psychological Association (APA)
López-Alarcón, Mardia& Perichart-Perera, Otilia& Flores-Huerta, Samuel& Inda-Icaza, Patricia& Bram-Falcón, María Teresa& Mayorga-Ochoa, Marielle…[et al.]. 2014. Excessive Refined Carbohydrates and Scarce Micronutrients Intakes Increase Inflammatory Mediators and Insulin Resistance in Prepubertal and Pubertal Obese Children Independently of Obesity. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043847
Modern Language Association (MLA)
Bram-Falcón, María Teresa…[et al.]. Excessive Refined Carbohydrates and Scarce Micronutrients Intakes Increase Inflammatory Mediators and Insulin Resistance in Prepubertal and Pubertal Obese Children Independently of Obesity. Mediators of Inflammation No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1043847
American Medical Association (AMA)
López-Alarcón, Mardia& Perichart-Perera, Otilia& Flores-Huerta, Samuel& Inda-Icaza, Patricia& Bram-Falcón, María Teresa& Mayorga-Ochoa, Marielle…[et al.]. Excessive Refined Carbohydrates and Scarce Micronutrients Intakes Increase Inflammatory Mediators and Insulin Resistance in Prepubertal and Pubertal Obese Children Independently of Obesity. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043847