Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation
Joint Authors
Liu, Haibo
Xiaofang, Guo
Chunming, Wang
Jie, Yuan
Guozhong, Chen
Limei, Zhang
Yong, Cao
Yu, Fang
Yingchun, Bao
Wangjun, Yu
Ge, Jun-Bo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP).
Our aim was to assess the prognostic value of PTX3 in patients with stable coronary artery disease (CAD) after drug eluting stent (DES) implantation.
Plasma PTX3 levels were measured before percutaneous coronary intervention (PCI) and at 24 h post-PCI in 596 consecutive patients with stable CAD.
Patients were followed up for a median of 3 years (range 1–5) for major adverse cardiovascular events (MACEs).
We found that the post-PCI plasma PTX3 levels were significantly higher at 24 h after PCI than pre-PCI, patients with MACEs had higher post-PCI PTX3 levels compared with MACEs-free patients, patients with higher post-PCI PTX3 levels (median > 4.384 ng/mL) had a higher risk for MACEs than those with PTX3 < 4.384 ng/mL, and post-PCI PTX3, cTnI, multiple stents, and age but not high-sensitivity CRP (hsCRP) were independently associated with the prevalence of MACEs after DES implantation.
The present study shows that post-PCI PTX3 may be a more reliable inflammatory predictor of long-term MACEs in patients with stable CAD undergoing DES implantation than CRP.
Measurement of post-PCI PTX3 levels could provide a rationale for risk stratification of patients with stable CAD after DES implantation.
American Psychological Association (APA)
Liu, Haibo& Xiaofang, Guo& Chunming, Wang& Jie, Yuan& Guozhong, Chen& Limei, Zhang…[et al.]. 2014. Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043924
Modern Language Association (MLA)
Liu, Haibo…[et al.]. Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation. Mediators of Inflammation No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1043924
American Medical Association (AMA)
Liu, Haibo& Xiaofang, Guo& Chunming, Wang& Jie, Yuan& Guozhong, Chen& Limei, Zhang…[et al.]. Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043924
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043924