Bedside Tested Ocular Motor Disorders in Multiple Sclerosis Patients
Joint Authors
Castelnovo, Giovanni
Renard, Dimitri
Taieb, G.
Labauge, P.
Bastide, S.
Zorzon, Marino
Servillo, Giovanna
Source
Multiple Sclerosis International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background/Aims.
Ocular motor disorders (OMDs) are a common feature of multiple sclerosis (MS).
In clinical practice, if not reported by patients, OMDs are often underdiagnosed and their prevalence is underestimated.
Methods.
We studied 163 patients (125 women, 76.7%, 38 men, 23.3%; median age 45.0 years; median disease duration 10 years; median EDSS 3.5) with definite MS ( n = 150 , 92%) or clinically isolated syndrome ( n = 13 , 8%) who underwent a thorough clinical examination of eye movements.
Data on localization of previous relapses, MS subtype, and MRI findings were collected and analyzed.
Results.
Overall, 111/163 (68.1%) patients showed at least one abnormality of eye movement.
Most frequent OMDs were impaired smooth pursuit (42.3%), saccadic dysmetria (41.7%), unilateral internuclear ophthalmoplegia (14.7%), slowing of saccades (14.7%), skew deviation (13.5%), and gaze evoked nystagmus (13.5%).
Patients with OMDs had more severe disability ( P = 0.0005 ) and showed more frequently infratentorial MRI lesions ( P = 0.004 ) .
Localization of previous relapses was not associated with presence of OMDs.
Conclusion.
OMDs are frequent in patients with stable (no relapses) MS.
A precise bedside examination of eye motility can disclose abnormalities that imply the presence of subclinical MS lesions and may have a substantial impact on definition of the diagnosis and on management of MS patients.
American Psychological Association (APA)
Servillo, Giovanna& Renard, Dimitri& Taieb, G.& Labauge, P.& Bastide, S.& Zorzon, Marino…[et al.]. 2014. Bedside Tested Ocular Motor Disorders in Multiple Sclerosis Patients. Multiple Sclerosis International،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1046611
Modern Language Association (MLA)
Servillo, Giovanna…[et al.]. Bedside Tested Ocular Motor Disorders in Multiple Sclerosis Patients. Multiple Sclerosis International No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1046611
American Medical Association (AMA)
Servillo, Giovanna& Renard, Dimitri& Taieb, G.& Labauge, P.& Bastide, S.& Zorzon, Marino…[et al.]. Bedside Tested Ocular Motor Disorders in Multiple Sclerosis Patients. Multiple Sclerosis International. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1046611
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046611