![](/images/graphics-bg.png)
Modulation of Cortical Interhemispheric Interactions by Motor Facilitation or Restraint
Joint Authors
Castelo-Branco, Miguel
Vidal, Ana Cristina
Banca, Paula
Pascoal, Augusto Gil
Cordeiro, Gustavo
Sargento-Freitas, João
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cortical interhemispheric interactions in motor control are still poorly understood and it is important to clarify how these depend on inhibitory/facilitatory limb movements and motor expertise, as reflected by limb dominance.
Here we addressed this problem using functional magnetic resonance imaging (fMRI) and a task involving dominant/nondominant limb mobilization in the presence/absence of contralateral limb restraint.
In this way we could modulate excitation/deactivation of the contralateral hemisphere.
Blocks of arm elevation were alternated with absent/present restraint of the contralateral limb in 17 participants.
We found the expected activation of contralateral sensorimotor cortex and ipsilateral cerebellum during arm elevation.
In addition, only the dominant arm elevation (hold period) was accompanied by deactivation of ipsilateral sensorimotor cortex, irrespective of presence/absence of contralateral restraint, although the latter increased deactivation.
In contrast, the nondominant limb yielded absent deactivation and reduced area of contralateral activation upon restriction.
Our results provide evidence for a difference in cortical communication during motor control (action facilitation/inhibition), depending on the “expertise” of the hemisphere that controls action (dominant versus nondominant).
These results have relevant implications for the development of facilitation/inhibition strategies in neurorehabilitation, namely, in stroke, given that fMRI deactivations have recently been shown to reflect decreases in neural responses.
American Psychological Association (APA)
Vidal, Ana Cristina& Banca, Paula& Pascoal, Augusto Gil& Cordeiro, Gustavo& Sargento-Freitas, João& Castelo-Branco, Miguel. 2014. Modulation of Cortical Interhemispheric Interactions by Motor Facilitation or Restraint. Neural Plasticity،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1046657
Modern Language Association (MLA)
Vidal, Ana Cristina…[et al.]. Modulation of Cortical Interhemispheric Interactions by Motor Facilitation or Restraint. Neural Plasticity No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1046657
American Medical Association (AMA)
Vidal, Ana Cristina& Banca, Paula& Pascoal, Augusto Gil& Cordeiro, Gustavo& Sargento-Freitas, João& Castelo-Branco, Miguel. Modulation of Cortical Interhemispheric Interactions by Motor Facilitation or Restraint. Neural Plasticity. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1046657
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046657