Cytokines in Bipolar Disorder: Paving the Way for Neuroprogression
Joint Authors
Barbosa, Izabela Guimarães
Bauer, Moisés Evandro
Machado-Vieira, Rodrigo
Teixeira, Antonio Lucio
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Bipolar disorder (BD) is a severe, chronic, and recurrent psychiatric illness.
It has been associated with high prevalence of medical comorbidities and cognitive impairment.
Its neurobiology is not completely understood, but recent evidence has shown a wide range of immune changes.
Cytokines are proteins involved in the regulation and the orchestration of the immune response.
We performed a review on the involvement of cytokines in BD.
We also discuss the cytokines involvement in the neuroprogression of BD.
It has been demonstrated that increased expression of cytokines in the central nervous system in postmortem studies is in line with the elevated circulating levels of proinflammatory cytokines in BD patients.
The proinflammatory profile and the immune imbalance in BD might be regarded as potential targets to the development of new therapeutic strategies.
American Psychological Association (APA)
Barbosa, Izabela Guimarães& Bauer, Moisés Evandro& Machado-Vieira, Rodrigo& Teixeira, Antonio Lucio. 2014. Cytokines in Bipolar Disorder: Paving the Way for Neuroprogression. Neural Plasticity،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1046682
Modern Language Association (MLA)
Barbosa, Izabela Guimarães…[et al.]. Cytokines in Bipolar Disorder: Paving the Way for Neuroprogression. Neural Plasticity No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1046682
American Medical Association (AMA)
Barbosa, Izabela Guimarães& Bauer, Moisés Evandro& Machado-Vieira, Rodrigo& Teixeira, Antonio Lucio. Cytokines in Bipolar Disorder: Paving the Way for Neuroprogression. Neural Plasticity. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1046682
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046682