Abnormal Baseline Brain Activity in Patients with Pulsatile Tinnitus: A Resting-State fMRI Study
Joint Authors
Han, Lv
Zhaohui, Liu
Fei, Yan
Ting, Li
Pengfei, Zhao
Wang, Du
Cheng, Dong
Pengde, Guo
Xiaoyi, Han
Xiao, Wang
Rui, Li
Zhenchang, Wang
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Numerous investigations studying the brain functional activity of the tinnitus patients have indicated that neurological changes are important findings of this kind of disease.
However, the pulsatile tinnitus (PT) patients were excluded in previous studies because of the totally different mechanisms of the two subtype tinnitus.
The aim of this study is to investigate whether altered baseline brain activity presents in patients with PT using resting-state functional magnetic resonance imaging (rs-fMRI) technique.
The present study used unilateral PT patients (n=42) and age-, sex-, and education-matched normal control subjects (n=42) to investigate the changes in structural and amplitude of low-frequency (ALFF) of the brain.
Also, we analyzed the relationships between these changes with clinical data of the PT patients.
Compared with normal controls, PT patients did not show any structural changes.
PT patients showed significant increased ALFF in the bilateral precuneus, and bilateral inferior frontal gyrus (IFG) and decreased ALFF in multiple occipital areas.
Moreover, the increased THI score and PT duration was correlated with increased ALFF in precuneus and bilateral IFG.
The abnormalities of spontaneous brain activity reflected by ALFF measurements in the absence of structural changes may provide insights into the neural reorganization in PT patients.
American Psychological Association (APA)
Han, Lv& Zhaohui, Liu& Fei, Yan& Ting, Li& Pengfei, Zhao& Wang, Du…[et al.]. 2014. Abnormal Baseline Brain Activity in Patients with Pulsatile Tinnitus: A Resting-State fMRI Study. Neural Plasticity،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1046708
Modern Language Association (MLA)
Han, Lv…[et al.]. Abnormal Baseline Brain Activity in Patients with Pulsatile Tinnitus: A Resting-State fMRI Study. Neural Plasticity No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1046708
American Medical Association (AMA)
Han, Lv& Zhaohui, Liu& Fei, Yan& Ting, Li& Pengfei, Zhao& Wang, Du…[et al.]. Abnormal Baseline Brain Activity in Patients with Pulsatile Tinnitus: A Resting-State fMRI Study. Neural Plasticity. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1046708
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046708