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Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review
Joint Authors
Rehman, Yasir
Rehman, Nadia
Rehman, Riaz
Source
Neurology Research International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Besides brain injury and systemic infection, cognitive and concussion like sickness behaviour is associated with muscular trauma and perioperative patients, which represents a major obstacle to daily activities and rehabilitation.
The neuroinflammatory response triggers glial activation and consequently the release of proinflammatory cytokines within the hippocampus.
We review clinical studies that have investigated neurocognitive and psychosomatic symptoms related to muscular trauma and in perioperative conditions.
These include impaired attention and executive and general cognitive functioning.
The purpose of this literature review is to focus on the systemic inflammation and the role of proinflammatory cytokines IL1, IL6,and TNF and other inflammatory mediators which mediates the cognitive impairment and induces sickness behaviour.
Moreover, this review will also help to determine if some patients could have long-term cognitive changes associated with musculoskeletal injuries or as a consequence of surgery and thereby will lead to efforts in reducing that risk.
American Psychological Association (APA)
Rehman, Yasir& Rehman, Nadia& Rehman, Riaz. 2014. Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review. Neurology Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1046791
Modern Language Association (MLA)
Rehman, Yasir…[et al.]. Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review. Neurology Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1046791
American Medical Association (AMA)
Rehman, Yasir& Rehman, Nadia& Rehman, Riaz. Peripheral Cytokines as a Chemical Mediator for Postconcussion Like Sickness Behaviour in Trauma and Perioperative Patients: Literature Review. Neurology Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1046791
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046791