![](/images/graphics-bg.png)
Does Maturity Affect Cephalic Perfusion and TQRS Ratio during Prolonged Umbilical Cord Occlusion in Fetal Sheep?
Joint Authors
Gunn, Alistair Jan
Bennet, Laura
Galinsky, Robert
Wassink, Guido
Drury, Paul P.
Gunn, Eleanor R.
Source
Obstetrics and Gynecology International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-16
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
T/QRS ratio monitoring is used to help identify fetal asphyxia.
However, immature animals have greater capacity to maintain blood pressure during severe asphyxia, raising the possibility that they may show an attenuated T/QRS increase during asphyxia.
Chronically instrumented fetal sheep at 0.6 of gestation (0.6 GA; n = 12), 0.7 GA (n = 12), and 0.8 GA (n = 8) underwent complete umbilical cord occlusion for 30 min, 25 min, or 15 min, respectively.
Cord occlusion was associated with progressive metabolic acidosis and initial hypertension followed by severe hypotension, with a more rapid fall in mean arterial blood pressure (MAP) and carotid blood flow (CaBF) with advancing gestation.
T/QRS ratio rose after occlusion more rapidly at 0.8 GA than in immature fetuses, to a similar final peak at all ages, followed by a progressive fall that was slower at 0.8 GA than in the immature fetuses.
The increase in T/QRS ratio correlated with initial hypertension at 0.8 GA ( P < 0.05 , R 2 = 0.38), and conversely, its fall correlated closely with falling MAP in all gestational groups ( P < 0.01 , R 2 = 0.67).
In conclusion, elevation of the T/QRS ratio is an index of onset of severe asphyxia in the last third of gestation, but not of fetal compromise.
American Psychological Association (APA)
Wassink, Guido& Galinsky, Robert& Drury, Paul P.& Gunn, Eleanor R.& Bennet, Laura& Gunn, Alistair Jan. 2014. Does Maturity Affect Cephalic Perfusion and TQRS Ratio during Prolonged Umbilical Cord Occlusion in Fetal Sheep?. Obstetrics and Gynecology International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1046889
Modern Language Association (MLA)
Wassink, Guido…[et al.]. Does Maturity Affect Cephalic Perfusion and TQRS Ratio during Prolonged Umbilical Cord Occlusion in Fetal Sheep?. Obstetrics and Gynecology International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1046889
American Medical Association (AMA)
Wassink, Guido& Galinsky, Robert& Drury, Paul P.& Gunn, Eleanor R.& Bennet, Laura& Gunn, Alistair Jan. Does Maturity Affect Cephalic Perfusion and TQRS Ratio during Prolonged Umbilical Cord Occlusion in Fetal Sheep?. Obstetrics and Gynecology International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1046889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046889