Correlation between Serum RANTES Levels and the Severity of Parkinson’s Disease
Joint Authors
Tang, Peng
Chong, Li
Li, Xiaoqing
Liu, Yue
Liu, Peng
Hou, Chen
Li, Rui
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Inflammatory mediators may reflect a role of systemic inflammation in the neurodegenerative process of Parkinson’s disease (PD).
Interleukin-6 (IL-6) and chemokine ligand 5 (CCL5), also known as RANTES (regulated on activation, normal T cell expressed and secreted), have been implicated in neurodegenerative diseases including PD.
Serum levels of RANTES and IL-6 of 78 consecutive PD patients and age-matched 80 controls were measured.
Patients with PD had higher RANTES and IL-6 levels compared with the controls.
We found that serum RANTES levels strongly correlated with Hoehn-Yahr score and disease duration in PD patients.
This study indicated that patients with PD have an on-going systemic inflammatory profile where the elevated peripheral production of RANTES may play a role in the neurodegenerative process.
American Psychological Association (APA)
Tang, Peng& Chong, Li& Li, Xiaoqing& Liu, Yue& Liu, Peng& Hou, Chen…[et al.]. 2014. Correlation between Serum RANTES Levels and the Severity of Parkinson’s Disease. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1046962
Modern Language Association (MLA)
Tang, Peng…[et al.]. Correlation between Serum RANTES Levels and the Severity of Parkinson’s Disease. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1046962
American Medical Association (AMA)
Tang, Peng& Chong, Li& Li, Xiaoqing& Liu, Yue& Liu, Peng& Hou, Chen…[et al.]. Correlation between Serum RANTES Levels and the Severity of Parkinson’s Disease. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1046962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1046962