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Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults
Joint Authors
Li, Yanli
Browne, Richard W.
Bonner, Matthew R.
Deng, Furong
Tian, Lili
Mu, Lina
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Human evidence is limited regarding the interaction between oxidative stress biomarkers and chemokines, especially in a population of adults without overt clinical disease.
The current study aims to examine the possible relationships of antioxidant and lipid peroxidation markers with several chemokines in adults.
Methods.
We assessed cross-sectional associations of total antioxidant status (TAS) and two lipid peroxidation markers malondialdehyde (MDA) and thiobarbituric acid reactive substances (TBARS) with a suite of serum chemokines, including CXCL-1 (GRO- α ), CXCL-8 (IL-8), CXCL-10 (IP-10), CCL-2 (MCP-1), CCL-5 (RANTES), CCL-8 (MCP-2), CCL-11 (Eotaxin-1), and CCL-17 (TARC), among 104 Chinese adults without serious preexisting clinical conditions in Beijing before 2008 Olympics.
Results.
TAS showed significantly positive correlations with MCP-1 ( r = 0.15751 , P = 0.0014 ), MCP-2 ( r = 0.3721 , P = 0.0001 ), Eotaxin-1 ( r = 0.39598 , P < 0 .
0001 ), and TARC ( r = 0.27149 , P = 0.0053 ).
The positive correlations remained unchanged after controlling for age, sex, body mass index, smoking, and alcohol drinking status.
No associations were found between any of the chemokines measured in this study and MDA or TBARS.
Similar patterns were observed when the analyses were limited to nonsmokers.
Conclusion.
Total antioxidant status is positively associated with several chemokines in this adult population.
American Psychological Association (APA)
Li, Yanli& Browne, Richard W.& Bonner, Matthew R.& Deng, Furong& Tian, Lili& Mu, Lina. 2014. Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047089
Modern Language Association (MLA)
Li, Yanli…[et al.]. Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047089
American Medical Association (AMA)
Li, Yanli& Browne, Richard W.& Bonner, Matthew R.& Deng, Furong& Tian, Lili& Mu, Lina. Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047089
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047089