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Fumigant Activity of the Psidium guajava Var. Pomifera (Myrtaceae) Essential Oil in Drosophila melanogaster by Means of Oxidative Stress
Joint Authors
Douglas Melo Coutinho, Henrique
Franco, Jeferson Luis
Posser, Thaís
Cruz, L. C.
Nunes, M. E. M.
Pinho, Antonio Ivanildo
Wallau, Gabriel Luz
Leite, Nadghia Figueiredo
da Cunha, Francisco Assis Bezerra
Costa, José Galberto Martins da
Tintino, Saulo R.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The guava fruit, Psidium guajava var.
pomifera (Myrtaceae family), is a native plant from South America.
Its leaves and fruits are widely used in popular medicine in tropical and subtropical countries.
Drosophila melanogaster has been used as one of the main model organisms in genetic studies since the 1900s.
The extensive knowledge about this species makes it one of the most suitable organisms to study many aspects of toxic compound effects.
Due to the lack of studies on the effects of the bioactive compounds present in the P.
guajava var.
pomifera essential oil, we performed a phytochemical characterization by CG-MS and evaluated the toxicity induced by the essential oil in the D.
melanogaster insect model.
In order to understand the biochemical mechanisms of toxicity, changes on the Nrf2 signaling as well as hallmarks of oxidative stress response were followed in the exposed flies.
Our results showed that exposure of insects to the P.
guajava oil increased mortality and locomotor deficits in parallel with an oxidative stress response signaling.
Therefore, it suggested a bioinsecticidal activity for P.
guajava volatile compounds by means of oxidative stress.
Further studies are ongoing to identify which oil compounds are responsible for such effect.
American Psychological Association (APA)
Pinho, Antonio Ivanildo& Wallau, Gabriel Luz& Nunes, M. E. M.& Leite, Nadghia Figueiredo& Tintino, Saulo R.& Cruz, L. C.…[et al.]. 2014. Fumigant Activity of the Psidium guajava Var. Pomifera (Myrtaceae) Essential Oil in Drosophila melanogaster by Means of Oxidative Stress. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047090
Modern Language Association (MLA)
Pinho, Antonio Ivanildo…[et al.]. Fumigant Activity of the Psidium guajava Var. Pomifera (Myrtaceae) Essential Oil in Drosophila melanogaster by Means of Oxidative Stress. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1047090
American Medical Association (AMA)
Pinho, Antonio Ivanildo& Wallau, Gabriel Luz& Nunes, M. E. M.& Leite, Nadghia Figueiredo& Tintino, Saulo R.& Cruz, L. C.…[et al.]. Fumigant Activity of the Psidium guajava Var. Pomifera (Myrtaceae) Essential Oil in Drosophila melanogaster by Means of Oxidative Stress. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047090
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047090