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Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study
Joint Authors
Gómez-Oliván, Leobardo Manuel
Miranda-Mendoza, Gerardo Daniel
Cabrera-Galeana, Paula Anel
Galar-Martínez, Marcela
Islas-Flores, Hariz
SanJuan-Reyes, Nely
Neri-Cruz, Nadia
García-Medina, Sandra
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The impact of involuntary exposure to antineoplastic drugs (AD) was studied in a group of nurses in diverse hospitals in Mexico.
The results were compared with a group of unexposed nurses.
Anthropometric characteristics and the biochemical analysis were analyzed in both groups.
Also, lipid peroxidation level (LPX), protein carbonyl content (PCC), and activity of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were evaluated in blood of study participants as oxidative stress (OS) biomarkers.
The group of occupationally exposed (OE) nurses consisted of 30 individuals ranging in age from 25 to 35 years.
The control group included 30 nurses who were not occupationally exposed to the preparation and handling of AD and whose anthropometric and biochemical characteristics were similar to those of the OE group.
All biomarkers evaluated were significantly increased ( P < 0.5 ) in OE nurses compared to the control group.
Results show that the assessment of OS biomarkers is advisable in order to evaluate exposure to AD in nurses.
American Psychological Association (APA)
Gómez-Oliván, Leobardo Manuel& Miranda-Mendoza, Gerardo Daniel& Cabrera-Galeana, Paula Anel& Galar-Martínez, Marcela& Islas-Flores, Hariz& SanJuan-Reyes, Nely…[et al.]. 2014. Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047150
Modern Language Association (MLA)
Gómez-Oliván, Leobardo Manuel…[et al.]. Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1047150
American Medical Association (AMA)
Gómez-Oliván, Leobardo Manuel& Miranda-Mendoza, Gerardo Daniel& Cabrera-Galeana, Paula Anel& Galar-Martínez, Marcela& Islas-Flores, Hariz& SanJuan-Reyes, Nely…[et al.]. Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047150