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Robotic Prostatectomy Has a Superior Outcome in Larger Prostates and PSA Density Is a Strong Predictor of Biochemical Recurrence
Joint Authors
Vasdev, Nikhil
Bishara, S.
Lane, T.
Adshead, J.
Boustead, Gregory
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
The aims of this study were to compare the outcomes of robotic assisted laparoscopic prostatectomy (RALP) between patients who had larger (≥75 g) and smaller (<75 g) prostates and to evaluate the performance of PSA density (PSAD) in determining the oncological outcome of surgery.
Methods and Materials.
344 patients who underwent RALP at a single institution were included in the study.
Preoperative risk factors and postoperative, oncological outcomes, erectile function, and continence status were recorded prospectively.
Results.
During a mean follow-up of 20 months, biochemical recurrence PSA>0.2 was observed in 15 patients (4.3%).
Prostate size ≥75 g was associated with lower Gleason score on final pathology P=0.004 and lower pathological stage P=0.02 but an increased length of hospital stay P=0.05.
PSAD on binary logistic regression independently predicted biochemical recurrence (BCR) when defined as postoperative PSA >0.1 P=0.001 and PSA >0.2 P=0.039.
In both instances PSA was no longer a significant independent predictor.
Conclusions.
RALP in large prostates (≥75 g, <150 g) is as safe as RALP in smaller prostates and is associated with a lower pathological grade and stage.
Higher PSAD is independently associated with BCR and is superior to PSA as a predictor of BCR after RALP.
American Psychological Association (APA)
Bishara, S.& Vasdev, Nikhil& Lane, T.& Boustead, Gregory& Adshead, J.. 2014. Robotic Prostatectomy Has a Superior Outcome in Larger Prostates and PSA Density Is a Strong Predictor of Biochemical Recurrence. Prostate Cancer،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047195
Modern Language Association (MLA)
Bishara, S.…[et al.]. Robotic Prostatectomy Has a Superior Outcome in Larger Prostates and PSA Density Is a Strong Predictor of Biochemical Recurrence. Prostate Cancer No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047195
American Medical Association (AMA)
Bishara, S.& Vasdev, Nikhil& Lane, T.& Boustead, Gregory& Adshead, J.. Robotic Prostatectomy Has a Superior Outcome in Larger Prostates and PSA Density Is a Strong Predictor of Biochemical Recurrence. Prostate Cancer. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047195