Mortality in Levodopa-Treated Parkinson's Disease
Joint Authors
Morgan, John C.
Currie, Lillian J.
Harrison, Madaline B.
Bennett, James P.
Trugman, Joel M.
Wooten, G. Frederick
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Parkinson’s disease (PD) is associated with increased mortality despite many advances in treatment.
Following the introduction of levodopa in the late 1960’s, many studies reported improved or normalized mortality rates in PD.
Despite the remarkable symptomatic benefits provided by levodopa, multiple recent studies have demonstrated that PD patients continue to die at a rate in excess of their peers.
We undertook this retrospective study of 211 deceased PD patients to determine the factors associated with mortality in levodopa-treated PD.
Our findings confirm that PD is associated with increased mortality in both men and women.
Unlike the majority of other mortality studies, we found that women have a greater reduction in lifespan compared to men.
We also found that patients with early onset PD (onset at the age of 50 or before) have reduced survival relative to PD patients with later ages of onset.
A final important finding is that survival is equal in PD patients treated with levodopa early (within 2 years or less of PD onset) versus later.
American Psychological Association (APA)
Morgan, John C.& Currie, Lillian J.& Harrison, Madaline B.& Bennett, James P.& Trugman, Joel M.& Wooten, G. Frederick. 2014. Mortality in Levodopa-Treated Parkinson's Disease. Parkinson’s Disease،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047206
Modern Language Association (MLA)
Morgan, John C.…[et al.]. Mortality in Levodopa-Treated Parkinson's Disease. Parkinson’s Disease No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1047206
American Medical Association (AMA)
Morgan, John C.& Currie, Lillian J.& Harrison, Madaline B.& Bennett, James P.& Trugman, Joel M.& Wooten, G. Frederick. Mortality in Levodopa-Treated Parkinson's Disease. Parkinson’s Disease. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047206
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047206