Nonmotor Symptoms in a Malaysian Parkinson’s Disease Population
Joint Authors
Khairul Anuar, Abdul Manaf
Shah, Shamsul Azhar
Hanita, Othman
Nafisah, Wan Yahya
Norlinah, Mohamed Ibrahim
Tan, Hui Jan
Raymond, Azman Ali
Azmin, Shahrul
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The nonmotor symptoms are important determinants of health and quality of life in Parkinson’s disease but are not well recognized and addressed in clinical practice.
This study was conducted to determine the prevalence of nonmotor symptoms and their impact on quality of life in patients with Parkinson’s disease.
Methods.
This was a cross-sectional study among patients with idiopathic Parkinson’s disease.
Exclusion criteria were a Mini Mental State Examination score of <21/30.
Prevalence of nonmotor symptoms was determined using the NMSQuest.
The severity of nonmotor symptoms and the quality of life were assessed using validated disease-specific questionnaires (PDQ-39 and NMSS).
Results.
A total of 113 patients consisting of 60 males and 53 females were recruited.
The median duration of illness was 5.0 (2.0–8.0) years.
The prevalence rate of nonmotor symptoms in our cohort was 97.3%.
The most common reported nonmotor symptom in our cohort was gastrointestinal (76.1%).
We found that the severity of the nonmotor symptoms was associated with poorer quality of life scores ( r s : 0.727, P < 0.001 ).
Conclusions.
Nonmotor symptoms were highly prevalent in our patients with Parkinson’s disease and adversely affected the quality of life of our patients.
In contrast to western studies, the most common nonmotor symptom is gastrointestinal.
The possibility of an Asian diet playing a role in this observation requires further study.
American Psychological Association (APA)
Azmin, Shahrul& Khairul Anuar, Abdul Manaf& Tan, Hui Jan& Nafisah, Wan Yahya& Raymond, Azman Ali& Hanita, Othman…[et al.]. 2014. Nonmotor Symptoms in a Malaysian Parkinson’s Disease Population. Parkinson’s Disease،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047209
Modern Language Association (MLA)
Azmin, Shahrul…[et al.]. Nonmotor Symptoms in a Malaysian Parkinson’s Disease Population. Parkinson’s Disease No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1047209
American Medical Association (AMA)
Azmin, Shahrul& Khairul Anuar, Abdul Manaf& Tan, Hui Jan& Nafisah, Wan Yahya& Raymond, Azman Ali& Hanita, Othman…[et al.]. Nonmotor Symptoms in a Malaysian Parkinson’s Disease Population. Parkinson’s Disease. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047209
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047209