Comparison of the Psychological Symptoms and Disease-Specific Quality of Life between Early- and Typical-Onset Parkinson’s Disease Patients
Joint Authors
Farhadi, Farzaneh
Shahidi, Gholam Ali
Hadizadeh, Hasti
Lökk, Johan
Delbari, Ahmad
Fereshtehnejad, Seyed-Mohammad
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The impact of Parkinson’s disease (PD) on psychological status and quality of life (QoL) may vary depending on age of disease onset.
The aim of this study was to compare psychological symptoms and disease-specific QoL between early onset versus the rest of the PD patients.
A total number of 140 PD patients with the mean current age of 61.3 (SD=10.4) yr were recruited in this study.
PD patients with the onset age of ≤50 yr were defined as “early-onset” (EOPD) group (n=45), while the ones with >50 yr at the time of diagnosis were categorized as the “typical-onset” (TOPD) patients (n=95).
Different questionnaires and scales were used for between-group comparisons including PDQ39, HADS (hospital anxiety and depression scale), FSS (fatigue severity scale), MNA (mininutritional assessment), and the UPDRS.
Depression score was significantly higher in EOPD group (6.3 (SD=4.5) versus 4.5 (SD=4.2), P=0.02).
Among different domains of QoL, emotion score was also significantly higher in the EOPD group (32.3 (SD=21.6) versus 24.4 (SD=22.7), P=0.05).
Our findings showed more severe depression and more impaired emotional domain of QoL in early-onset PD patients.
Depression and anxiety play an important role to worsen QoL among both EOPD and TOPD patients, while no interaction was observed in the efficacy of these two psychiatric symptoms and the onset age of PD patients.
American Psychological Association (APA)
Fereshtehnejad, Seyed-Mohammad& Hadizadeh, Hasti& Farhadi, Farzaneh& Shahidi, Gholam Ali& Delbari, Ahmad& Lökk, Johan. 2014. Comparison of the Psychological Symptoms and Disease-Specific Quality of Life between Early- and Typical-Onset Parkinson’s Disease Patients. Parkinson’s Disease،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047222
Modern Language Association (MLA)
Fereshtehnejad, Seyed-Mohammad…[et al.]. Comparison of the Psychological Symptoms and Disease-Specific Quality of Life between Early- and Typical-Onset Parkinson’s Disease Patients. Parkinson’s Disease No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1047222
American Medical Association (AMA)
Fereshtehnejad, Seyed-Mohammad& Hadizadeh, Hasti& Farhadi, Farzaneh& Shahidi, Gholam Ali& Delbari, Ahmad& Lökk, Johan. Comparison of the Psychological Symptoms and Disease-Specific Quality of Life between Early- and Typical-Onset Parkinson’s Disease Patients. Parkinson’s Disease. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047222