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Biomarkers to Improve Diagnosis and Monitoring of Obstructive Sleep Apnea Syndrome: Current Status and Future Perspectives
Joint Authors
Papanas, Nikolaos
Archontogeorgis, Kostas
Nena, Evangelia
Steiropoulos, Paschalis
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-27
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of upper airway collapse associated with oxygen desaturation and sleep disruption.
It is proposed that these periodic changes lead to molecular variations that can be detected by assessing serum biomarkers.
Studies have identified inflammatory, oxidative, and metabolic perturbations attributable to sleep-disordered breathing.
Given that OSAS is associated with increased cardiovascular and cerebrovascular morbidity, the ideal biomarker should enable timely recognition with the possibility of intervention.
There is accumulating data on the utility of serum biomarkers for the evaluation of disease severity, prognosis, and response to treatment.
However, current knowledge is limited by data collection techniques, disease complexity, and potential confounding factors.
The current paper reviews the literature on the use of serum biomarkers in OSAS.
It is concluded that the ideal serum biomarker still needs to be discovered, while caution is needed in the interpretation of hitherto available results.
American Psychological Association (APA)
Archontogeorgis, Kostas& Nena, Evangelia& Papanas, Nikolaos& Steiropoulos, Paschalis. 2014. Biomarkers to Improve Diagnosis and Monitoring of Obstructive Sleep Apnea Syndrome: Current Status and Future Perspectives. Pulmonary Medicine،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1047264
Modern Language Association (MLA)
Archontogeorgis, Kostas…[et al.]. Biomarkers to Improve Diagnosis and Monitoring of Obstructive Sleep Apnea Syndrome: Current Status and Future Perspectives. Pulmonary Medicine No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1047264
American Medical Association (AMA)
Archontogeorgis, Kostas& Nena, Evangelia& Papanas, Nikolaos& Steiropoulos, Paschalis. Biomarkers to Improve Diagnosis and Monitoring of Obstructive Sleep Apnea Syndrome: Current Status and Future Perspectives. Pulmonary Medicine. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1047264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047264