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Changes in Renal Function in Elderly Patients Following Intravenous Iodinated Contrast Administration: A Retrospective Study
Joint Authors
Alsafi, Ali
Alsafi, Zaid
Lakhani, Amish
Strickland, Nicola H.
Source
Radiology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Contrast-induced nephropathy (CIN) is a recognised complication of intravascular administration of iodinated contrast media (ICM).
Previous studies suggest a higher incidence in the elderly, but no large study has assessed this to date.
We set out to assess changes in creatinine in elderly inpatients following computed tomography (CT) examination and compare those who received intravenous contrast to those who did not.
Methods.
Using the Radiology Information System in two teaching hospitals, inpatients over the age of seventy who had a CT examination and a baseline creatinine were identified and their follow-up creatinine levels were analysed.
Elderly inpatients who underwent a noncontrast CT over the same period were used as controls.
Results.
677 elderly inpatients who received ICM were compared with 487 controls.
9.2% of patients who received ICM developed acute kidney injury (AKI) compared to 3.5% of inpatient controls ( P < 0.0001 ).
Patients with higher baseline eGFR had a higher incidence of post-CT AKI.
Conclusions.
The incidence of post-CT AKI is higher in patients who received IV ICM compared to those who did not; the difference may be partly attributable to contrast-induced nephropathy.
This suggests that the incidence of CIN in the elderly may not be as high as previously thought.
American Psychological Association (APA)
Alsafi, Ali& Alsafi, Zaid& Lakhani, Amish& Strickland, Nicola H.. 2014. Changes in Renal Function in Elderly Patients Following Intravenous Iodinated Contrast Administration: A Retrospective Study. Radiology Research and Practice،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1047425
Modern Language Association (MLA)
Alsafi, Ali…[et al.]. Changes in Renal Function in Elderly Patients Following Intravenous Iodinated Contrast Administration: A Retrospective Study. Radiology Research and Practice No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1047425
American Medical Association (AMA)
Alsafi, Ali& Alsafi, Zaid& Lakhani, Amish& Strickland, Nicola H.. Changes in Renal Function in Elderly Patients Following Intravenous Iodinated Contrast Administration: A Retrospective Study. Radiology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1047425
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047425