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Differential Diagnoses of Overgrowth Syndromes: The Most Important Clinical and Radiological Disease Manifestations
Joint Authors
Lacerda, Letícia da Silva
Alves, Úrsula David
Zanier, José Fernando Cardona
Machado, Dequitier Carvalho
Camilo, Gustavo Bittencourt
Lopes, Agnaldo José
Source
Radiology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Overgrowth syndromes comprise a heterogeneous group of diseases that are characterized by excessive tissue development.
Some of these syndromes may be associated with dysfunction in the receptor tyrosine kinase (RTK)/PI3K/AKT pathway, which results in an increased expression of the insulin receptor.
In the current review, four overgrowth syndromes were characterized (Proteus syndrome, Klippel-Trenaunay-Weber syndrome, Madelung’s disease, and neurofibromatosis type I) and illustrated using cases from our institution.
Because these syndromes have overlapping clinical manifestations and have no established genetic tests for their diagnosis, radiological methods are important contributors to the diagnosis of many of these syndromes.
The correlation of genetic discoveries and molecular pathways that may contribute to the phenotypic expression is also of interest, as this may lead to potential therapeutic interventions.
American Psychological Association (APA)
Lacerda, Letícia da Silva& Alves, Úrsula David& Zanier, José Fernando Cardona& Machado, Dequitier Carvalho& Camilo, Gustavo Bittencourt& Lopes, Agnaldo José. 2014. Differential Diagnoses of Overgrowth Syndromes: The Most Important Clinical and Radiological Disease Manifestations. Radiology Research and Practice،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047439
Modern Language Association (MLA)
Lacerda, Letícia da Silva…[et al.]. Differential Diagnoses of Overgrowth Syndromes: The Most Important Clinical and Radiological Disease Manifestations. Radiology Research and Practice No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1047439
American Medical Association (AMA)
Lacerda, Letícia da Silva& Alves, Úrsula David& Zanier, José Fernando Cardona& Machado, Dequitier Carvalho& Camilo, Gustavo Bittencourt& Lopes, Agnaldo José. Differential Diagnoses of Overgrowth Syndromes: The Most Important Clinical and Radiological Disease Manifestations. Radiology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047439
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047439