MRI-Based Assessment of Safe Margins in Tumor Surgery
Joint Authors
Cartiaux, Olivier
Banse, Xavier
Schubert, Thomas
Galant, Christine
Lecouvet, Frederic
Bellanova, Laura
Docquier, Pierre-Louis
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
In surgical oncology, histological analysis of excised tumor specimen is the conventional method to assess the safety of the resection margins.
We tested the feasibility of using MRI to assess the resection margins of freshly explanted tumor specimens in rats.
Materials and Methods.
Fourteen specimen of sarcoma were resected in rats and analysed both with MRI and histologically.
Slicing of the specimen was identical for the two methods and corresponding slices were paired.
498 margins were measured in length and classified using the UICC classification (R0, R1, and R2).
Results.
The mean difference between the 498 margins measured both with histology and MRI was 0.3 mm (SD 1.0 mm).
The agreement interval of the two measurement methods was [−1.7 mm; 2.2 mm].
In terms of the UICC classification, a strict correlation was observed between MRI- and histology-based classifications ( κ = 0.84 , P < 0.05 ).
Discussion.
This experimental study showed the feasibility to use MRI images of excised tumor specimen to assess the resection margins with the same degree of accuracy as the conventional histopathological analysis.
When completed, MRI acquisition of resected tumors may alert the surgeon in case of inadequate margin and help advantageously the histopathological analysis.
American Psychological Association (APA)
Bellanova, Laura& Schubert, Thomas& Cartiaux, Olivier& Lecouvet, Frederic& Galant, Christine& Banse, Xavier…[et al.]. 2014. MRI-Based Assessment of Safe Margins in Tumor Surgery. Complexity،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1047456
Modern Language Association (MLA)
Bellanova, Laura…[et al.]. MRI-Based Assessment of Safe Margins in Tumor Surgery. Complexity Vol. 2014, no. 2014 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1047456
American Medical Association (AMA)
Bellanova, Laura& Schubert, Thomas& Cartiaux, Olivier& Lecouvet, Frederic& Galant, Christine& Banse, Xavier…[et al.]. MRI-Based Assessment of Safe Margins in Tumor Surgery. Complexity. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1047456
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047456