Acupoint Injection of Autologous Stromal Vascular Fraction and Allogeneic Adipose-Derived Stem Cells to Treat Hip Dysplasia in Dogs
Joint Authors
Marx, Camila
Silveira, Maiele Dornelles
Selbach, Isabel
da Silva, Ariel Silveira
Braga, Luisa Maria Gomes de Macedo
Camassola, Melissa
Nardi, Nance Beyer
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-11
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Stem cells isolated from adipose tissue show great therapeutic potential in veterinary medicine, but some points such as the use of fresh or cultured cells and route of administration need better knowledge.
This study aimed to evaluate the effect of autologous stromal vascular fraction (SVF, n = 4 ) or allogeneic cultured adipose-derived stem cells (ASCs, n = 5 ) injected into acupuncture points in dogs with hip dysplasia and weak response to drug therapy.
Canine ASCs have proliferation and differentiation potential similar to ASCs from other species.
After the first week of treatment, clinical evaluation showed marked improvement compared with baseline results in all patients treated with autologous SVF and three of the dogs treated with allogeneic ASCs.
On days 15 and 30, all dogs showed improvement in range of motion, lameness at trot, and pain on manipulation of the joints, except for one ASC-treated patient.
Positive results were more clearly seen in the SVF-treated group.
These results show that autologous SVF or allogeneic ASCs can be safely used in acupoint injection for treating hip dysplasia in dogs and represent an important therapeutic alternative for this type of pathology.
Further studies are necessary to assess a possible advantage of SVF cells in treating joint diseases.
American Psychological Association (APA)
Marx, Camila& Silveira, Maiele Dornelles& Selbach, Isabel& da Silva, Ariel Silveira& Braga, Luisa Maria Gomes de Macedo& Camassola, Melissa…[et al.]. 2014. Acupoint Injection of Autologous Stromal Vascular Fraction and Allogeneic Adipose-Derived Stem Cells to Treat Hip Dysplasia in Dogs. Stem Cells International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047511
Modern Language Association (MLA)
Marx, Camila…[et al.]. Acupoint Injection of Autologous Stromal Vascular Fraction and Allogeneic Adipose-Derived Stem Cells to Treat Hip Dysplasia in Dogs. Stem Cells International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047511
American Medical Association (AMA)
Marx, Camila& Silveira, Maiele Dornelles& Selbach, Isabel& da Silva, Ariel Silveira& Braga, Luisa Maria Gomes de Macedo& Camassola, Melissa…[et al.]. Acupoint Injection of Autologous Stromal Vascular Fraction and Allogeneic Adipose-Derived Stem Cells to Treat Hip Dysplasia in Dogs. Stem Cells International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047511