Immune Response in Thyroid Cancer: Widening the Boundaries
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-24
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
The association between thyroid cancer and thyroid inflammation has been repeatedly reported and highly debated in the literature.
In fact, both molecular and epidemiological data suggest that these diseases are closely related and this association reinforces that the immune system is important for thyroid cancer progression.
Innate immunity is the first line of defensive response.
Unlike innate immune responses, adaptive responses are highly specific to the particular antigen that induced them.
Both branches of the immune system may interact in antitumor immune response.
Major effector cells of the immune system that directly target thyroid cancer cells include dendritic cells, macrophages, polymorphonuclear leukocytes, mast cells, and lymphocytes.
A mixture of immune cells may infiltrate thyroid cancer microenvironment and the balance of protumor and antitumor activity of these cells may be associated with prognosis.
Herein, we describe some evidences that immune response may be important for thyroid cancer progression and may help us identify more aggressive tumors, sparing the vast majority of patients from costly unnecessary invasive procedures.
The future trend in thyroid cancer is an individualized therapy.
American Psychological Association (APA)
Ward, Laura Sterian. 2014. Immune Response in Thyroid Cancer: Widening the Boundaries. Scientifica،Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-1047542
Modern Language Association (MLA)
Ward, Laura Sterian. Immune Response in Thyroid Cancer: Widening the Boundaries. Scientifica No. 2014 (2014), pp.1-20.
https://search.emarefa.net/detail/BIM-1047542
American Medical Association (AMA)
Ward, Laura Sterian. Immune Response in Thyroid Cancer: Widening the Boundaries. Scientifica. 2014. Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-1047542
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047542