Prevalence of blaNDM, blaPER, blaVEB, blaIMP, and blaVIM Genes among Acinetobacter baumannii Isolated from Two Hospitals of Tehran, Iran
Joint Authors
Fallah, Fatemeh
Noori, Maryam
Hashemi, Ali
Goudarzi, Hossein
Karimi, Abdollah
Erfanimanesh, Soroor
Alimehr, Shadi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and Objectives.
The aim of this study was to determine the frequency of blaNDM, blaPER, blaVEB, blaIMP, and blaVIM type genes among A.
baumannii isolates from hospitalized patients in two hospitals in Tehran, Iran.
Patients and Methods.
Antibiotic susceptibility tests were performed by Kirby-Bauer disc diffusion and Broth microdilution methods.
The frequency of MBL (metallo-beta-lactamase) and ESBL (extended-spectrum-beta-lactamase) producers was evaluated by CDDT.
The β-lactamases genes were detected by PCR and sequencing methods.
Results.
The resistance of A.
baumannii isolates against tested antibiotics was as follows: 103 (95.4%) to ceftazidime, 108 (100%) to cefotaxime, 105 (95.7%) to cefepime, 99 (91.7%) to imipenem, 99 (91.7%) to meropenem, 87 (80.6%) to amikacin, 105 (97.2%) to piperacillin, 100 (92.6%) to ciprofloxacin, 103 (95.4%) to piperacillin/tazobactam, 44 (40.7%) to gentamicin, 106 (98.1%) to ampicillin/sulbactam, 106 (98.1%) to co-trimoxazole, 87 (80.6%) to tetracycline, and 1 (1.8%) to colistin.
Using combined disk diffusion test, 91 (84.2%) and 86 (86.86%) were ESBL and MBL producers, respectively.
The prevalence of blaPER-1, blaVEB-1, blaIMP-1, and blaVIM-1 genes was 71 (78.03%), 36 (39.5%), 3 (3.48%), and 15 (17.44%), respectively.
Conclusions.
The prevalence of ESBLs and MBLs-producing A.
baumannii strains detected in this study is a major concern and highlights the need of infection control measures.
American Psychological Association (APA)
Fallah, Fatemeh& Noori, Maryam& Hashemi, Ali& Goudarzi, Hossein& Karimi, Abdollah& Erfanimanesh, Soroor…[et al.]. 2014. Prevalence of blaNDM, blaPER, blaVEB, blaIMP, and blaVIM Genes among Acinetobacter baumannii Isolated from Two Hospitals of Tehran, Iran. Scientifica،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047552
Modern Language Association (MLA)
Fallah, Fatemeh…[et al.]. Prevalence of blaNDM, blaPER, blaVEB, blaIMP, and blaVIM Genes among Acinetobacter baumannii Isolated from Two Hospitals of Tehran, Iran. Scientifica No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047552
American Medical Association (AMA)
Fallah, Fatemeh& Noori, Maryam& Hashemi, Ali& Goudarzi, Hossein& Karimi, Abdollah& Erfanimanesh, Soroor…[et al.]. Prevalence of blaNDM, blaPER, blaVEB, blaIMP, and blaVIM Genes among Acinetobacter baumannii Isolated from Two Hospitals of Tehran, Iran. Scientifica. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047552
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047552