Human Interferon Alpha-2b: A Therapeutic Protein for Cancer Treatment
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Human interferon alpha (hIFN α ) is a wide biological activity cytokine that is used in hepatitis and cancer treatments.
It regulates many genes that are involved in antiviral and antiproliferative activities.
This mini review focuses on human interferon alpha-2b (hIFN α -2b) as therapeutic protein for cancer treatment.
The review covers hIFN α -2b molecular characteristic and its molecular mechanism by Janus activated kinase/signal transducer activation of transcription (JAK-STAT) pathway.
The JAK-STAT pathway regulates not only proteins involved in inhibition of proliferation but also apoptosis.
As additional discussion of clinical applications, the use of recombinant hIFN α -2b (rhIFN α -2b) as therapeutic protein in several types of cancer is also explained.
American Psychological Association (APA)
Asmana Ningrum, Ratih. 2014. Human Interferon Alpha-2b: A Therapeutic Protein for Cancer Treatment. Scientifica،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047612
Modern Language Association (MLA)
Asmana Ningrum, Ratih. Human Interferon Alpha-2b: A Therapeutic Protein for Cancer Treatment. Scientifica No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1047612
American Medical Association (AMA)
Asmana Ningrum, Ratih. Human Interferon Alpha-2b: A Therapeutic Protein for Cancer Treatment. Scientifica. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047612
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047612