Elevated Cardiac Troponin in Acute Stroke without Acute Coronary Syndrome Predicts Long-Term Adverse Cardiovascular Outcomes
Joint Authors
Raza, Farhan
Alkhouli, Mohamad
Sandhu, Paul
Bhatt, Reema
Bove, Alfred A.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Elevated cardiac troponin in acute stroke in absence of acute coronary syndrome (ACS) has unclear long-term outcomes.
Methods.
Retrospective analysis of 566 patients admitted to Temple University Hospital from 2008 to 2010 for acute stroke was performed.
Patients were included if cardiac troponin I was measured and had no evidence of ACS and an echocardiogram was performed.
Of 200 patients who met the criteria, baseline characteristics, electrocardiograms, and major adverse cardiovascular events (MACE) were reviewed.
Patients were characterized into two groups with normal and elevated troponins.
Primary end point was nonfatal myocardial infarction during follow-up period after discharge.
The secondary end points were MACE and death from any cause.
Results.
For 200 patients, 17 patients had positive troponins.
Baseline characteristics were as follows: age 63.1 ± 13.8 , 64% African Americans, 78% with hypertension, and 22% with previous CVA.
During mean follow-up of 20.1 months, 7 patients (41.2%) in elevated troponin and 6 (3.3%) patients in normal troponin group had nonfatal myocardial infarction ( P = 0.0001 ).
MACE (41.2% versus 14.2%, P = 0.01 ) and death from any cause (41.2% versus 14.5%, P = 0.017 ) were significant in the positive troponin group.
Conclusions.
Elevated cardiac troponin in patients with acute stroke and no evidence of ACS is strong predictor of long-term cardiac outcomes.
American Psychological Association (APA)
Raza, Farhan& Alkhouli, Mohamad& Sandhu, Paul& Bhatt, Reema& Bove, Alfred A.. 2014. Elevated Cardiac Troponin in Acute Stroke without Acute Coronary Syndrome Predicts Long-Term Adverse Cardiovascular Outcomes. Stroke Research and Treatment،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047701
Modern Language Association (MLA)
Raza, Farhan…[et al.]. Elevated Cardiac Troponin in Acute Stroke without Acute Coronary Syndrome Predicts Long-Term Adverse Cardiovascular Outcomes. Stroke Research and Treatment No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047701
American Medical Association (AMA)
Raza, Farhan& Alkhouli, Mohamad& Sandhu, Paul& Bhatt, Reema& Bove, Alfred A.. Elevated Cardiac Troponin in Acute Stroke without Acute Coronary Syndrome Predicts Long-Term Adverse Cardiovascular Outcomes. Stroke Research and Treatment. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047701