Prognostic Factors in Tuberculosis Related Mortalities in Hospitalized Patients
Joint Authors
Haque, Ghazal
Kumar, Ashok
Saifuddin, Fatima
Ismail, Shafaq
Rizvi, Nadeem
Ghazal, Shaista
Notani, Sadhna
Source
Tuberculosis Research and Treatment
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Setting.
The study was undertaken at the Department of Pulmonology at a public, tertiary care centre in Karachi, Pakistan.
Objectives.
To evaluate factors concerned with in-hospital deaths in patients admitted with pulmonary tuberculosis (TB).
Design.
A retrospective case-control audit was performed for 120 patients hospitalised with pulmonary TB.
Sixty of those discharged after treatment were compared to sixty who did not survive.
Radiological findings, clinical indicators, and laboratory values were compared between the two groups to identify factors related to poor prognosis.
Results.
Factors concerned with in-hospital mortality listed late presentation of disease (P<0.01), noncompliance to antituberculosis therapy (P<0.01), smoking (P<0.01), longer duration of illness prior to treatment (P<0.01), and low body weight (P<0.01).
Most deaths occurred during the first week of admission (P<0.01) indicating late referrals as significant.
Immunocompromised status and multi-drug resistance were not implicated in higher mortality.
Conclusions.
Poor prognosis was associated with noncompliance to therapy resulting in longer duration of illness, late patient referrals to care centres, and development of complications.
Early diagnosis, timely referrals, and monitored compliance may help reduce mortality.
Adherence to a more radically effective treatment regimen is required to eliminate TB early during disease onset.
American Psychological Association (APA)
Haque, Ghazal& Kumar, Ashok& Saifuddin, Fatima& Ismail, Shafaq& Rizvi, Nadeem& Ghazal, Shaista…[et al.]. 2014. Prognostic Factors in Tuberculosis Related Mortalities in Hospitalized Patients. Tuberculosis Research and Treatment،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048068
Modern Language Association (MLA)
Haque, Ghazal…[et al.]. Prognostic Factors in Tuberculosis Related Mortalities in Hospitalized Patients. Tuberculosis Research and Treatment No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1048068
American Medical Association (AMA)
Haque, Ghazal& Kumar, Ashok& Saifuddin, Fatima& Ismail, Shafaq& Rizvi, Nadeem& Ghazal, Shaista…[et al.]. Prognostic Factors in Tuberculosis Related Mortalities in Hospitalized Patients. Tuberculosis Research and Treatment. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048068
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048068