Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers: Preliminary Study of the Calcification Potential
Joint Authors
Stancu, Izabela-Cristina
Vasile, E.
Petre, D.
Giol, D.
Dubruel, P.
Iovu, Horia
Serafim, Andrada
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-28
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Gold-dendrimer nanocomposites were obtained for the first time by a simple colloidal approach based on the use of polyamidoamine dendrimers with succinamic acid terminal groups and dodecanediamine core.
Spherical and highly crystalline nanoparticles with dimensions between 3 nm and 60 nm, and size-polydispersity depending on the synthesis conditions, have been generated.
The influence of the stoichiometric ratio and the structural and architectural features of the dendrimers on the properties of the nanocomposites has been described.
The self-assembling behaviour of these materials produces gold-dendrimer nanostructured porous networks with variable density, porosity, and composition.
The investigations of the reaction systems, by TEM, at two postsynthesis moments, allowed to preliminary establish the control over the properties of the nanocomposite products.
Furthermore, this study allowed better understanding of the mechanism of nanocomposite generation.
Impressively, in the early stages of the synthesis, the organization of gold inside the dendrimer molecules has been evidenced by micrographs.
Growth and ripening mechanisms further lead to nanoparticles with typical characteristics.
The potential of such nanocomposite particles to induce calcification when coating a polymer substrate was also investigated.
American Psychological Association (APA)
Vasile, E.& Serafim, Andrada& Petre, D.& Giol, D.& Dubruel, P.& Iovu, Horia…[et al.]. 2014. Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers: Preliminary Study of the Calcification Potential. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1048287
Modern Language Association (MLA)
Vasile, E.…[et al.]. Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers: Preliminary Study of the Calcification Potential. The Scientific World Journal No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1048287
American Medical Association (AMA)
Vasile, E.& Serafim, Andrada& Petre, D.& Giol, D.& Dubruel, P.& Iovu, Horia…[et al.]. Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers: Preliminary Study of the Calcification Potential. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1048287
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048287