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Evaluation of the Inhibition of Carbohydrate Hydrolyzing Enzymes, the Antioxidant Activity, and the Polyphenolic Content of Citrus limetta Peel Extract
Joint Authors
Padilla-Camberos, Eduardo
Flores-Fernández, José Miguel
Lazcano-Díaz, Estefania
Owolabi, Moses S.
Allen, Kirk
Villanueva-Rodríguez, Socorro
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Type 2 diabetes mellitus is one of the most frequent causes of death in Mexico, characterized by chronic hyperglycemia.
One alternative strategy for this metabolic abnormality is inhibiting the enzymes responsible for the metabolism of carbohydrates.
We evaluated whether the aqueous Citrus limetta peel extract could inhibit the metabolism of carbohydrates.
We found that this extract inhibited primarily the enzyme α-amylase by 49.6% at a concentration of 20 mg/mL and to a lesser extent the enzyme α-glucosidase with an inhibition of 28.2% at the same concentration.
This inhibition is likely due to the high polyphenol content in the Citrus limetta peel (19.1 mg GAE/g).
Antioxidant activity of the Citrus limetta peel demonstrated dose-dependent antioxidant activity, varying from 6.5% at 1.125 mg/mL to 42.5% at 20 mg/mL.
The study of these polyphenolic compounds having both antihyperglycemic and antioxidant activities may provide a new approach to the management of type 2 diabetes mellitus.
American Psychological Association (APA)
Padilla-Camberos, Eduardo& Lazcano-Díaz, Estefania& Flores-Fernández, José Miguel& Owolabi, Moses S.& Allen, Kirk& Villanueva-Rodríguez, Socorro. 2014. Evaluation of the Inhibition of Carbohydrate Hydrolyzing Enzymes, the Antioxidant Activity, and the Polyphenolic Content of Citrus limetta Peel Extract. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1048361
Modern Language Association (MLA)
Padilla-Camberos, Eduardo…[et al.]. Evaluation of the Inhibition of Carbohydrate Hydrolyzing Enzymes, the Antioxidant Activity, and the Polyphenolic Content of Citrus limetta Peel Extract. The Scientific World Journal No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1048361
American Medical Association (AMA)
Padilla-Camberos, Eduardo& Lazcano-Díaz, Estefania& Flores-Fernández, José Miguel& Owolabi, Moses S.& Allen, Kirk& Villanueva-Rodríguez, Socorro. Evaluation of the Inhibition of Carbohydrate Hydrolyzing Enzymes, the Antioxidant Activity, and the Polyphenolic Content of Citrus limetta Peel Extract. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1048361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048361