Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method

Abstract EN

In this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized.

Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method.

The silver doped hydroxyapatite thin films were characterized by various techniques such as Scanning electron microscopy (SEM) with energy Dispersive X-ray attachment (X-EDS), Fourier transform infrared spectroscopy (FT-IR), and glow discharge optical emission spectroscopy (GDOES).

These techniques have permitted the structural and chemical characterisation of the silver doped hydroxyapatite thin films.

The antimicrobial effect of the Ag:HAp thin films on Escherichia coli and Staphylococcus aureus bacteria was then investigated.

This is the first study on the antimicrobial effect of Ag:HAp thin films obtained by sol-gel method.

The results of this study have shown that the Ag:HAp thin films with xAg=0.5 are effective against E.

coli and S.

aureus after 24 h.