Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies
Joint Authors
Lanati, Niccolò
Brondino, Natascia
Boldrini, Annalisa
Cuccomarino, Antonella
Barale, Francesco
Re, Simona
Politi, Pierluigi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Dementia is a leading health problem worldwide, with Alzheimer’s disease (AD) representing up to 60% of all dementia cases.
A growing interest has recently risen on the potential use of natural molecules in this condition.
Curcumin is a polyphenolic compound traditionally used in Indian medicine.
Several in vitro and in vivo studies have found a protective effect of curcumin in AD.
In the present systematic review we aimed to evaluate the state-of-the-art of clinical trials of curcumin in AD.
We retrieved three published studies, while there are several ongoing clinical trials.
To date there is insufficient evidence to suggest the use of curcumin in dementia patients.
Of note, short-term use of curcumin appears to be safe.
Several reasons could be responsible for the discrepancy between in vitro and in vivo findings and human trials, such as low bioavailability and poor study design.
American Psychological Association (APA)
Brondino, Natascia& Re, Simona& Boldrini, Annalisa& Cuccomarino, Antonella& Lanati, Niccolò& Barale, Francesco…[et al.]. 2014. Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048596
Modern Language Association (MLA)
Brondino, Natascia…[et al.]. Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1048596
American Medical Association (AMA)
Brondino, Natascia& Re, Simona& Boldrini, Annalisa& Cuccomarino, Antonella& Lanati, Niccolò& Barale, Francesco…[et al.]. Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048596
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048596