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Can Na18F PETCT Be Used to Study Bone Remodeling in the Tibia When Patients Are Being Treated with a Taylor Spatial Frame?
Joint Authors
Weidenhielm, Lars
Lundblad, Henrik
Maguire, Gerald Q.
Olivecrona, Henrik
Jonsson, Cathrine
Jacobsson, Hans
Zeleznik, Michael P.
Sundin, Anders
Noz, Marilyn E.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Monitoring and quantifying bone remodeling are of interest, for example, in correction osteotomies, delayed fracture healing pseudarthrosis, bone lengthening, and other instances.
Seven patients who had operations to attach an Ilizarov-derived Taylor Spatial Frame to the tibia gave informed consent.
Each patient was examined by Na18F PET/CT twice, at approximately six weeks and three months after the operation.
A validated software tool was used for the following processing steps.
The first and second CT volumes were aligned in 3D and the respective PET volumes were aligned accordingly.
In the first PET volume spherical volumes of interest (VOIs) were delineated for the crural fracture and normal bone and transferred to the second PET volume for SUVmax evaluation.
This method potentially provides clinical insight into questions such as, when has the bone remodeling progressed well enough to safely remove the TSF? and when is intervention required, in a timelier manner than current methods? For example, in two patients who completed treatment, the SUVmax between the first and second PET/CT examination decreased by 42% and 13%, respectively.
Further studies in a larger patient population are needed to verify these preliminary results by correlating regional Na18F PET measurements to clinical and radiological findings.
American Psychological Association (APA)
Lundblad, Henrik& Maguire, Gerald Q.& Olivecrona, Henrik& Jonsson, Cathrine& Jacobsson, Hans& Noz, Marilyn E.…[et al.]. 2014. Can Na18F PETCT Be Used to Study Bone Remodeling in the Tibia When Patients Are Being Treated with a Taylor Spatial Frame?. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1048902
Modern Language Association (MLA)
Lundblad, Henrik…[et al.]. Can Na18F PETCT Be Used to Study Bone Remodeling in the Tibia When Patients Are Being Treated with a Taylor Spatial Frame?. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1048902
American Medical Association (AMA)
Lundblad, Henrik& Maguire, Gerald Q.& Olivecrona, Henrik& Jonsson, Cathrine& Jacobsson, Hans& Noz, Marilyn E.…[et al.]. Can Na18F PETCT Be Used to Study Bone Remodeling in the Tibia When Patients Are Being Treated with a Taylor Spatial Frame?. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1048902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048902