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A Quantitative Method for the Characterization of Lytic Metastases of the Bone from Radiographic Images
Joint Authors
Baltasar Sánchez, Alicia
Gonzalez Sistal, Angel
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The aim of our study was to assess the diagnostic usefulness of the gray level parameters to distinguish osteolytic lesions using radiological images.
Materials and Methods.
A retrospective study was carried out.
A total of 76 skeletal radiographs of osteolytic metastases and 67 radiographs of multiple myeloma were used.
The cases were classified into nonflat (MM1 and OL1) and flat bones (MM2 and OL2).
These radiological images were analyzed by using a computerized method.
The parameters calculated were mean, standard deviation, and coefficient of variation (MGL, SDGL, and CVGL) based on gray level histogram analysis of a region-of-interest.
Diagnostic utility was quantified by measurement of parameters on osteolytic metastases and multiple myeloma, yielding quantification of area under the receiver operating characteristic (ROC) curve (AUC).
Results.
Flat bone groups (MM2 and OL2) showed significant differences in mean values of MGL (P=0.048) and SDGL (P=0.003).
Their corresponding values of AUC were 0.758 for MGL and 0.883 for SDGL in flat bones.
In nonflat bones these gray level parameters do not show diagnostic ability.
Conclusion.
The gray level parameters MGL and SDGL show a good discriminatory diagnostic ability to distinguish between multiple myeloma and lytic metastases in flat bones.
American Psychological Association (APA)
Baltasar Sánchez, Alicia& Gonzalez Sistal, Angel. 2014. A Quantitative Method for the Characterization of Lytic Metastases of the Bone from Radiographic Images. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1048967
Modern Language Association (MLA)
Baltasar Sánchez, Alicia& Gonzalez Sistal, Angel. A Quantitative Method for the Characterization of Lytic Metastases of the Bone from Radiographic Images. The Scientific World Journal No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1048967
American Medical Association (AMA)
Baltasar Sánchez, Alicia& Gonzalez Sistal, Angel. A Quantitative Method for the Characterization of Lytic Metastases of the Bone from Radiographic Images. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1048967
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048967