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Flavonoids in Juglans regia L. Leaves and Evaluation of In Vitro Antioxidant Activity via Intracellular and Chemical Methods
Joint Authors
Zhao, Ming-Hui
Jiang, Zi-Tao
Liu, Tao
Li, Rong
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Flavonoids are rich in Juglans regia L.
leaves.
They have potent antioxidant properties, which have been related to regulating immune function and enhancing anticancer activity.
Herein, qualitative and quantitative determination of flavonoids from J.
regia leaves was carried out using high performance liquid chromatography coupled with tandem mass spectrometry with electrospray ionization and negative ion detection (HPLC-ESI-MS/MS) by comparison of the retention times and mass spectral fragments with standard substances or related literatures.
Seventeen compounds were identified and major components are quercetin-3-O-rhamnoside (453.11 μg/g, dry weight), quercetin-3-O-arabinoside (73.91 μg/g), quercetin-3-O-xyloside (70.04 μg/g), kaempferol-O-pentoside derivative (49.04 μg/g), quercetin-3-O-galactoside (48.61 μg/g), and kaempferol-O-pentoside (48.46 μg/g).
The in vitro intracellular antioxidation indicated that flavonoids from J.
regia leaves could reduce the reactive oxygen species (ROS) level in RAW264.7 cells and showed good radical scavenging activities.
These results proved to be more related to the flavonoids that could be considered in the design of new formulations of dietary supplements or functional foods.
American Psychological Association (APA)
Zhao, Ming-Hui& Jiang, Zi-Tao& Liu, Tao& Li, Rong. 2014. Flavonoids in Juglans regia L. Leaves and Evaluation of In Vitro Antioxidant Activity via Intracellular and Chemical Methods. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049142
Modern Language Association (MLA)
Zhao, Ming-Hui…[et al.]. Flavonoids in Juglans regia L. Leaves and Evaluation of In Vitro Antioxidant Activity via Intracellular and Chemical Methods. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1049142
American Medical Association (AMA)
Zhao, Ming-Hui& Jiang, Zi-Tao& Liu, Tao& Li, Rong. Flavonoids in Juglans regia L. Leaves and Evaluation of In Vitro Antioxidant Activity via Intracellular and Chemical Methods. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049142
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049142