Anesthetic Techniques and Cancer Recurrence after Surgery
Joint Authors
Fodale, Vincenzo
D’Arrigo, Maria G.
Triolo, Stefania
Mondello, Stefania
La Torre, Domenico
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Many of the most common anesthetics are used in surgical oncology, yet effects on cancer cells are still not known.
Anesthesia technique could differentially affect cancer recurrence in oncologic patients undergoing surgery, due to immunosuppression, stimulation of angiogenesis, and dissemination of residual cancer cells.
Data support the use of intravenous anesthetics, such as propofol anesthesia, thanks to antitumoral protective effects inhibiting cyclooxygenase 2 and prostaglandins E2 in cancer cells, and stimulation of immunity response; a restriction in the use of volatile anesthetics; restriction in the use of opioids as they suppress humoral and cellular immunity, and their chronic use favors angiogenesis and development of metastases; use of locoregional anesthesia compared with general anesthesia, as locoregional appears to reduce cancer recurrence after surgery.
However, these findings must be interpreted cautiously as there is no evidence that simple changes in the practice of anesthesia can have a positive impact on postsurgical survival of cancer patients.
American Psychological Association (APA)
Fodale, Vincenzo& D’Arrigo, Maria G.& Triolo, Stefania& Mondello, Stefania& La Torre, Domenico. 2014. Anesthetic Techniques and Cancer Recurrence after Surgery. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1049235
Modern Language Association (MLA)
Fodale, Vincenzo…[et al.]. Anesthetic Techniques and Cancer Recurrence after Surgery. The Scientific World Journal No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1049235
American Medical Association (AMA)
Fodale, Vincenzo& D’Arrigo, Maria G.& Triolo, Stefania& Mondello, Stefania& La Torre, Domenico. Anesthetic Techniques and Cancer Recurrence after Surgery. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1049235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049235