Prognostic Implication of Preoperative Behavior Changes in Patients with Primary High-Grade Meningiomas
Joint Authors
Vranic, Andrej
Gilbert, Frederic
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
High-grade meningiomas are rare extra-axial tumors, frequently causing brain invasion and prominent brain edema.
Patients harboring high-grade meningiomas occasionally present with behavior changes.
Data about frequency and prognostic importance of preoperative behavior changes in patients with high-grade meningiomas is missing.
86 patients with primary high-grade meningiomas were analyzed.
Statistical analysis was performed to determine correlation of preoperative behavior changes with tumor location, preoperative brain edema, tumor cleavability, tumor grade, Ki67 proliferation index, and microscopic brain invasion.
Survival analysis was performed.
30 (34.9%) patients presented with preoperative behavior changes.
These changes were more frequent with male patients ( P = 0.066 ) and patients older than 55 years ( P = 0.018 ).
They correlated with frontal location ( P = 0.013 ), tumor size ( P = 0.023 ), microscopic brain invasion ( P = 0.015 ), and brain edema ( P = 0.006 ).
Preoperative behavior changes did not correlate with duration of symptoms, tumor cleavability, tumor malignancy grade, and Ki67 proliferation index.
They were not significantly related to overall survival or recurrence-free survival of patients with primary high-grade meningiomas.
Preoperative behavior changes are frequent in patients harboring primary high-grade meningiomas.
They correlate with tumor size, microscopic brain invasion, and brain edema.
Preoperative behavior changes do not predict prognosis in patients with primary high-grade meningiomas.
American Psychological Association (APA)
Vranic, Andrej& Gilbert, Frederic. 2014. Prognostic Implication of Preoperative Behavior Changes in Patients with Primary High-Grade Meningiomas. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1049465
Modern Language Association (MLA)
Vranic, Andrej& Gilbert, Frederic. Prognostic Implication of Preoperative Behavior Changes in Patients with Primary High-Grade Meningiomas. The Scientific World Journal No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1049465
American Medical Association (AMA)
Vranic, Andrej& Gilbert, Frederic. Prognostic Implication of Preoperative Behavior Changes in Patients with Primary High-Grade Meningiomas. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1049465
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049465