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Microwave Assisted Synthesis, Spectral and Antifungal Studies of 2-Phenyl-N,N′-bis(pyridin-4-ylcarbonyl)butanediamide Ligand and Its Metal Complexes
Joint Authors
Malik, Maqsood Ahmad
Shiekh, Rayees Ahmad
Al-Thabaiti, Shaeel Ahmed
Nabi, Arshid
Wani, Mohmmad Younus
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
2-Phenyl-N,N′-bis(pyridin-4-ylcarbonyl)butanediamide ligand with a series of transition metal complexes has been synthesized via two routes: microwave irradiation and conventional heating method.
Microwave irritation method happened to be the efficient and versatile route for the synthesis of these metal complexes.
These complexes were found to have the general composition M(L)Cl2/M(L)(CH3COO)2 (where M = Cu(II), Co(II), Ni(II), and L = ligand).
Different physical and spectroscopic techniques were used to investigate the structural features of the synthesized compounds, which supported an octahedral geometry for these complexes.
In vitro antifungal activity of the ligand and its metal complexes revealed that the metal complexes are highly active compared to the standard drug.
Metal complexes showed enhanced activity compared to the ligand, which is an important step towards the designing of antifungal drug candidates.
American Psychological Association (APA)
Shiekh, Rayees Ahmad& Malik, Maqsood Ahmad& Al-Thabaiti, Shaeel Ahmed& Wani, Mohmmad Younus& Nabi, Arshid. 2014. Microwave Assisted Synthesis, Spectral and Antifungal Studies of 2-Phenyl-N,N′-bis(pyridin-4-ylcarbonyl)butanediamide Ligand and Its Metal Complexes. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1049487
Modern Language Association (MLA)
Shiekh, Rayees Ahmad…[et al.]. Microwave Assisted Synthesis, Spectral and Antifungal Studies of 2-Phenyl-N,N′-bis(pyridin-4-ylcarbonyl)butanediamide Ligand and Its Metal Complexes. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1049487
American Medical Association (AMA)
Shiekh, Rayees Ahmad& Malik, Maqsood Ahmad& Al-Thabaiti, Shaeel Ahmed& Wani, Mohmmad Younus& Nabi, Arshid. Microwave Assisted Synthesis, Spectral and Antifungal Studies of 2-Phenyl-N,N′-bis(pyridin-4-ylcarbonyl)butanediamide Ligand and Its Metal Complexes. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1049487
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049487