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An Assessment of Wound Healing Potential of Argyreia speciosa Leaves
Joint Authors
Yadav, Narayan Prasad
Rai, Vineet Kumar
Yadav, Kuldeep Singh
Rawat, Bindu
Shanker, Karuna
Venkateswara Rao, Chandana
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
In North India, poultice of young unfolded leaves of Argyreia speciosa Linn.
(Convolvulaceae) is used for healing wounds.
In order to find scientific evidence for the traditional utilization of leaves of A.
speciosa in wound healing, this investigation was carried out.
A linear incision wound of about 3 cm in length and 2 mm in depth and circular excision wound of 177 mm2 full thickness were made on the dorsal region of separate groups ( n = 5 ) of anesthetized Swiss albino mice.
A simple ointment, developed by including ethanol, ethanol-water, and water extracts (10% each, separately) of A.
speciosa, was applied topically to mice once daily for 14 days after wounding.
To evaluate the effect of each extract, wound contraction, epithelization period, wound breaking strength, and hydroxyproline content were determined.
The water extract of A.
speciosa showed accelerated wound healing activity as evidenced by fast wound contraction ( 96.30 ± 0.52 %; P < 0.01 ), rapid epithelization period ( 11.40 ± 0.60 days; P < 0.001 ), greater wound breaking strength ( 376.56 ± 21.16 g; P < 0.001 ), and higher hydroxyproline content ( 16.49 ± 1.12 mg/g; P < 0.05 ) of granulation tissue.
The present report supports the traditional use of Argyreia speciosa leaves for wound healing and signify its relevant therapeutic potential.
American Psychological Association (APA)
Yadav, Kuldeep Singh& Yadav, Narayan Prasad& Rawat, Bindu& Rai, Vineet Kumar& Shanker, Karuna& Venkateswara Rao, Chandana. 2014. An Assessment of Wound Healing Potential of Argyreia speciosa Leaves. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049500
Modern Language Association (MLA)
Yadav, Kuldeep Singh…[et al.]. An Assessment of Wound Healing Potential of Argyreia speciosa Leaves. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1049500
American Medical Association (AMA)
Yadav, Kuldeep Singh& Yadav, Narayan Prasad& Rawat, Bindu& Rai, Vineet Kumar& Shanker, Karuna& Venkateswara Rao, Chandana. An Assessment of Wound Healing Potential of Argyreia speciosa Leaves. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049500
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049500