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Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis
Joint Authors
Ristic-Medic, Danijela
Perunicic-Pekovic, Gordana
Rasic-Milutinovic, Zorica
Takic, Marija
Popovic, Tamara
Arsic, Aleksandra
Glibetic, Marija
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Background.
Plant seeds have gained interest for their health benefits due to their fatty acid content.
The objective of this study was to determine the effects of dietary consumption of milled sesame/pumpkin/flax seed mixture on glycemic control, serum lipids, phospholipid fatty acid status, and inflammatory factors in patients on hemodialysis.
Methods.
Thirty patients with well nutrition status (18 male, 12 female) were enrolled in the study.
Participants consumed 30 g of milled sesame/pumpkin/flax (6 g/6 g/18 g, resp.) seeds mixture added to their habitual diet.
Results.
Total n-6 and n-3 polyunsaturated fatty acids and levels of linoleic, dihomo-gamma-linolenic (DGLA), arachidonic, alpha-linolenic (ALA), eicosapentaenoic, docosapentaenoic, and docosahexaenoic (DHA) acid were increased after 12 weeks of supplementation.
A significant decrease of the serum triglyceride level (P<0.001), glucose, insulin, calculated IR HOMA (P<0.05), and inflammatory markers (TNF-alpha, IL-6, and hs-CRP, P<0.001) was observed after seed mixture treatment.
The serum levels of CRP and TNF-alpha negative correlate with ALA, DHA, and DGLA.
Conclusion.
Results of this study indicated that dietary milled sesame/pumpkin/flax seed mixture added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levels, affect glycemic control and improved fatty acid profile and pruritus symptoms in hemodialysis patients.
American Psychological Association (APA)
Ristic-Medic, Danijela& Perunicic-Pekovic, Gordana& Rasic-Milutinovic, Zorica& Takic, Marija& Popovic, Tamara& Arsic, Aleksandra…[et al.]. 2014. Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050113
Modern Language Association (MLA)
Ristic-Medic, Danijela…[et al.]. Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1050113
American Medical Association (AMA)
Ristic-Medic, Danijela& Perunicic-Pekovic, Gordana& Rasic-Milutinovic, Zorica& Takic, Marija& Popovic, Tamara& Arsic, Aleksandra…[et al.]. Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050113