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Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions
Joint Authors
Bębenek, Marcelina
Jelińska, Anna
Dołhań, Agnieszka
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Stability of ceftiofur sodium and cefquinome sulphate in intravenous solutions was studied.
Chromatographic separation and quantitative determination were performed by using a high-performance liquid chromatography with UV-DAD detection.
During the stability study, poly(vinylchloride) minibags were filled with a solution containing 5 mg of ceftiofur sodium or cefquinome sulphate and diluted to 0.2 mg/mL with suitable intravenous solution depending on the test conditions.
The solutions for the study were protected from light and stored at room temperature (22°C), refrigerated (6°C), frozen (−20°C) for 30 days, and then thawed at room temperature.
A comparison of results obtained at 22°C and 6°C for the same intravenous solutions showed that temperature as well as components of solutions and their concentration had an influence on the stability of ceftiofur sodium and cefquinome sulphate.
It was found that ceftiofur sodium and cefquinome sulphate dissolved in intravenous solutions used in this study may be stored at room temperature and at 6°C for up to 48 h.
American Psychological Association (APA)
Dołhań, Agnieszka& Jelińska, Anna& Bębenek, Marcelina. 2014. Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1050199
Modern Language Association (MLA)
Dołhań, Agnieszka…[et al.]. Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions. The Scientific World Journal No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1050199
American Medical Association (AMA)
Dołhań, Agnieszka& Jelińska, Anna& Bębenek, Marcelina. Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1050199
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050199