Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder
Joint Authors
Canpolat, Serpil
Kırpınar, İsmet
Deveci, Erdem
Aksoy, Hülya
Bayraktutan, Zafer
Eren, İbrahim
Demir, Recep
Selek, Salih
Aydın, Nazan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
We investigated the relationship of serum nitric oxide (NO) and asymmetrical dimethylarginine (ADMA) levels with cognitive functioning in patients with major depressive disorder (MDD).
41 MDD patients (Beck depression scale scores >16) and 44 controls were included in the study.
Rey verbal learning and memory test, auditory consonant trigram test, digit span test, Wisconsin card sorting test, continuous performance task (TOVA), and Stroop test scores were found to be impaired in patients with major depressive disorder when compared to healthy controls.
There was no significant difference between patient and control groups in terms of serum NO and ADMA.
Serum NO levels were correlated with TOVA test error scores and Stroop test time scores, whereas serum ADMA levels were negatively correlated with TOVA test error scores.
Metabolic detriments especially in relation to NO metabolism in frontal cortex and hypothalamus, psychomotor retardation, or loss of motivation may explain these deficits.
American Psychological Association (APA)
Canpolat, Serpil& Kırpınar, İsmet& Deveci, Erdem& Aksoy, Hülya& Bayraktutan, Zafer& Eren, İbrahim…[et al.]. 2014. Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050390
Modern Language Association (MLA)
Canpolat, Serpil…[et al.]. Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1050390
American Medical Association (AMA)
Canpolat, Serpil& Kırpınar, İsmet& Deveci, Erdem& Aksoy, Hülya& Bayraktutan, Zafer& Eren, İbrahim…[et al.]. Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050390
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050390