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Perinatal Stress, Fatigue, Depressive Symptoms, and Immune Modulation in Late Pregnancy and One Month Postpartum
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Stress and fatigue are common complaints of pregnant and postpartum women as is depression.
These symptoms may be related to immunomodulation.
However, few studies have examined these relationships.
The aim of this study was to examine the relationships among stress, fatigue, depression, and cytokines as markers of immune modulation in prenatal and postpartum women.
Women completed questionnaires and gave blood samples during late pregnancy and again at 4–6 weeks postpartum.
Blood was analyzed for cytokines as measures of immune modulation.
Stress, fatigue, and depression were experienced at moderately high levels, with higher levels of fatigue and depression in the postpartum but higher stress in the prenatal period.
Levels of several cytokines were increased in the postpartum over the prenatal period.
Stress and depression were related in the prenatal period and stress, depression, and fatigue were related in the postpartum.
While various cytokines were related to each other in both periods, only stress was related to MIP-1β, a cytokine that may be important for childbirth processes.
More studies, especially longitudinal and interventional studies, are needed to increase our knowledge about etiology, patterns, symptoms, factors, and management of maternal distress.
The search for reliable biomarkers for at-risk mothers remains a priority.
American Psychological Association (APA)
Cheng, C. Y.& Pickler, Rita H.. 2014. Perinatal Stress, Fatigue, Depressive Symptoms, and Immune Modulation in Late Pregnancy and One Month Postpartum. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050517
Modern Language Association (MLA)
Cheng, C. Y.& Pickler, Rita H.. Perinatal Stress, Fatigue, Depressive Symptoms, and Immune Modulation in Late Pregnancy and One Month Postpartum. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1050517
American Medical Association (AMA)
Cheng, C. Y.& Pickler, Rita H.. Perinatal Stress, Fatigue, Depressive Symptoms, and Immune Modulation in Late Pregnancy and One Month Postpartum. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050517
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050517