A Novel and Highly Regioselective Synthesis of New Carbamoylcarboxylic Acids from Dianhydrides
Joint Authors
Ochoa-Terán, Adrián
Estrada-Manjarrez, Jesús
Martínez-Quiroz, Marisela
Landey-Álvarez, Marco A.
Alcántar Zavala, Eleazar
Pina-Luis, Georgina
Santacruz Ortega, Hisila
Gómez-Pineda, Luis Enrique
Ramírez, José-Zeferino
Chávez, Daniel
Montes Ávila, Julio
Labastida-Galván, Victoria
Ordoñez, Mario
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-06
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
A regioselective synthesis has been developed for the preparation of a series of N,N′-disubstituted 4,4′-carbonylbis(carbamoylbenzoic) acids and N,N′-disubstituted bis(carbamoyl) terephthalic acids by treatment of 3,3′,4,4′-benzophenonetetracarboxylic dianhydride (1) and 1,2,4,5-benzenetetracarboxylic dianhydride (2) with arylalkyl primary amines (A-N).
The carbamoylcarboxylic acid derivatives were synthesized with good yield and high purity.
The specific reaction conditions were established to obtain carbamoyl and carboxylic acid functionalities over the thermodynamically most favored imide group.
Products derived from both anhydrides 1 and 2 were isolated as pure regioisomeric compounds under innovative experimental conditions.
The chemo- and regioselectivity of products derived from dianhydrides were determined by NMR spectroscopy and confirmed by density functional theory (DFT).
All products were characterized by NMR, FTIR, and MS.
American Psychological Association (APA)
Ochoa-Terán, Adrián& Estrada-Manjarrez, Jesús& Martínez-Quiroz, Marisela& Landey-Álvarez, Marco A.& Alcántar Zavala, Eleazar& Pina-Luis, Georgina…[et al.]. 2014. A Novel and Highly Regioselective Synthesis of New Carbamoylcarboxylic Acids from Dianhydrides. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1050792
Modern Language Association (MLA)
Ochoa-Terán, Adrián…[et al.]. A Novel and Highly Regioselective Synthesis of New Carbamoylcarboxylic Acids from Dianhydrides. The Scientific World Journal No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1050792
American Medical Association (AMA)
Ochoa-Terán, Adrián& Estrada-Manjarrez, Jesús& Martínez-Quiroz, Marisela& Landey-Álvarez, Marco A.& Alcántar Zavala, Eleazar& Pina-Luis, Georgina…[et al.]. A Novel and Highly Regioselective Synthesis of New Carbamoylcarboxylic Acids from Dianhydrides. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1050792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050792