Prediction of DNase I Hypersensitive Sites by Using Pseudo Nucleotide Compositions
Joint Authors
Jiang, Ning
Liu, Nan
Feng, Peng-Mian
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
DNase I hypersensitive sites (DHS) associated with a wide variety of regulatory DNA elements.
Knowledge about the locations of DHS is helpful for deciphering the function of noncoding genomic regions.
With the acceleration of genome sequences in the postgenomic age, it is highly desired to develop cost-effective computational methods to identify DHS.
In the present work, a support vector machine based model was proposed to identify DHS by using the pseudo dinucleotide composition.
In the jackknife test, the proposed model obtained an accuracy of 83%, which is competitive with that of the existing method.
This result suggests that the proposed model may become a useful tool for DHS identifications.
American Psychological Association (APA)
Feng, Peng-Mian& Jiang, Ning& Liu, Nan. 2014. Prediction of DNase I Hypersensitive Sites by Using Pseudo Nucleotide Compositions. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1050850
Modern Language Association (MLA)
Feng, Peng-Mian…[et al.]. Prediction of DNase I Hypersensitive Sites by Using Pseudo Nucleotide Compositions. The Scientific World Journal No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1050850
American Medical Association (AMA)
Feng, Peng-Mian& Jiang, Ning& Liu, Nan. Prediction of DNase I Hypersensitive Sites by Using Pseudo Nucleotide Compositions. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1050850
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050850