Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study
Joint Authors
Mravak-Stipetić, Marinka
Lončar-Brzak, Božana
Bakale-Hodak, Iva
Sabol, Ivan
Seiwerth, Sven
Majstorović, Martina
Grce, Magdalena
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different.
The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency.
Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and OLL diagnosis and to clarify which histopathologic criteria could best distinguish these two diagnoses.
A retrospective study showed that clinically diagnosed 92 OLPs and 14 OLLs have been confirmed histopathologically in 52.2% and 42.9% of cases, respectively.
In addition, histopathology showed statistically significant more eosinophils ( P < 0.0005 ), plasma cells ( P < 0.0005 ), and granulocytes ( P < 0.05 ) in OLL than OLP.
To establish histopathological diagnosis of OLP and OLL it should be mandatory to define the type of cells in mononuclear infiltrate, which can be associated more accurately with clinical feature and patient history.
Therefore, currently accepted diagnostic criteria for OLP and OLL should be modified and validated on a larger number of patients taking into account particular distinguishing histopathological features.
American Psychological Association (APA)
Mravak-Stipetić, Marinka& Lončar-Brzak, Božana& Bakale-Hodak, Iva& Sabol, Ivan& Seiwerth, Sven& Majstorović, Martina…[et al.]. 2014. Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1050883
Modern Language Association (MLA)
Mravak-Stipetić, Marinka…[et al.]. Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1050883
American Medical Association (AMA)
Mravak-Stipetić, Marinka& Lončar-Brzak, Božana& Bakale-Hodak, Iva& Sabol, Ivan& Seiwerth, Sven& Majstorović, Martina…[et al.]. Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1050883
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050883