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Evaluation of the Effect of Concurrent Chronic Total Occlusion and Successful Staged Revascularization on Long-Term Mortality in Patients with ST-Elevation Myocardial Infarction
Joint Authors
Zhou, Yingling
Shi, Guoxiang
He, Pengcheng
Liu, Yuanhui
Lin, Yaowang
Yang, Xing
Chen, Jiyuan
Tan, Ning
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Aims.
To investigate the impact of chronic total occlusion (CTO) in non-infarct-related artery (IRA) on the long-term prognosis and evaluate the clinical significance of staged revascularization in patients with ST-segment elevation myocardial infarction (STEMI).
Methods.
1266 STEMI patients with primary percutaneous coronary intervention (PCI) were categorized as single-vessel disease (SVD), multivessel disease (MVD) without and with CTO.
We study the clinical outcomes of patients after primary PCI in the following 3 years.
Additionally, patients with CTO received staged revascularization, and major adverse cardiac events (MACE) during 3-year follow-up were recorded.
Results.
Presence of CTO was a predictor of both early mortality [hazard ratio (HR) 3.4, 95% confidence interval (CI) 2.4–4.5, P < 0.01 ] and late mortality (HR 1.9, 95% CI 1.4–3.6, P < 0.01 ), whereas MVD without CTO was only a predictor of early mortality (HR 1.7, 95% CI 1.3–2.3, P < 0.05 ).
In CTO group, 100 patients had successful CTO recanalization, and 48 patients failed.
During 3-year follow-up, patients with failed procedure had higher cardiac mortality (22.9% versus 9.0%, P = 0.020 ) and lower MACE-free survival (50.0% versus 72.0%, P = 0.009 ) compared to patients with successful procedure.
Conclusion.
The presence of CTO and not MVD alone is associated with long-term mortality.
Successful revascularization of CTO in the non-IRA is associated with improved clinical outcomes in patients with STEMI undergoing primary PCI.
American Psychological Association (APA)
Shi, Guoxiang& He, Pengcheng& Liu, Yuanhui& Lin, Yaowang& Yang, Xing& Chen, Jiyuan…[et al.]. 2014. Evaluation of the Effect of Concurrent Chronic Total Occlusion and Successful Staged Revascularization on Long-Term Mortality in Patients with ST-Elevation Myocardial Infarction. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050926
Modern Language Association (MLA)
Shi, Guoxiang…[et al.]. Evaluation of the Effect of Concurrent Chronic Total Occlusion and Successful Staged Revascularization on Long-Term Mortality in Patients with ST-Elevation Myocardial Infarction. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1050926
American Medical Association (AMA)
Shi, Guoxiang& He, Pengcheng& Liu, Yuanhui& Lin, Yaowang& Yang, Xing& Chen, Jiyuan…[et al.]. Evaluation of the Effect of Concurrent Chronic Total Occlusion and Successful Staged Revascularization on Long-Term Mortality in Patients with ST-Elevation Myocardial Infarction. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050926
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050926