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The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea
Joint Authors
Koçer, Abdulkadir
Kilicarslan, Rukiye
Akkoyunlu, Muhammed Emin
Aralasmak, Ayse
Kart, Levent
Sharifov, Rasul
Alkan, Alpay
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Purpose.
We investigated diffusion alterations in specific regions of the brain in morbid obese, obese, and nonobese OSA patients and searched whether there is a correlation between BMI and ADC values.
Materials and Methods.
DWIs of 65 patients with OSA were evaluated.
The patients were classified according to BMI as morbid obese ( n = 16 ), obese ( n = 27 ), and nonobese (control, n = 22 ) groups.
ADC measurements were performed from 24 different regions of the brain in each patient.
The relationship of BMI with ADC values was searched.
Results.
The ADC values in hypothalamus, insular cortex, parietal cortex, caudate nucleus, frontal white matter, and posterior limb of internal capsule were all increased in obese patients ( n = 43 ) compared to control group.
The ADC values of midbrain, hypothalamus, orbitofrontal cortex, and parietal cortex were significantly increased in morbid obese compared to obese patients.
In obese patients, the degree of BMI was positively correlated with ADC values of orbitofrontal cortex, parietal cortex, and hypothalamus.
Conclusion.
We observed increasing brain vasogenic edema with increasing BMI, suggesting that the main reason of brain diffusion alteration in patients with OSA could be obesity related.
American Psychological Association (APA)
Kilicarslan, Rukiye& Alkan, Alpay& Sharifov, Rasul& Akkoyunlu, Muhammed Emin& Aralasmak, Ayse& Koçer, Abdulkadir…[et al.]. 2014. The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050980
Modern Language Association (MLA)
Kilicarslan, Rukiye…[et al.]. The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1050980
American Medical Association (AMA)
Kilicarslan, Rukiye& Alkan, Alpay& Sharifov, Rasul& Akkoyunlu, Muhammed Emin& Aralasmak, Ayse& Koçer, Abdulkadir…[et al.]. The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1050980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050980