Mink S38G Gene Polymorphism and Atrial Fibrillation in the Chinese Population: A Meta-Analysis of 1871 Participants
Joint Authors
Li, Yan-yan
Wang, Lian-sheng
Lu, Xin-zheng
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Mink gene S38G polymorphism in the β-subunit of slow activating component of the delayed rectifier potassium channel current potassium channel has been associated with increased atrial fibrillation (AF) risk.
However, the individual studies results were still controversial.
To investigate the association of Mink S38G gene polymorphisms with AF, a meta-analysis including 1871 subjects from six individual studies was conducted.
Mink S38G gene polymorphism was significantly related to AF under allelic (OR: 1.380, 95% CI: 1.200–1.600, P<0.00001), recessive (OR: 1.193, 95% CI: 1.033–1.377, P=0.017), dominant (OR: 1.057, 95% CI: 1.025–1.089, P<0.00001), additive (OR: 1.105, 95% CI: 1.036–1.178, P=0.002), homozygous (OR: 1.128, 95% CI: 1.068–1.191, P<0.00001), and heterozygous genetic models (OR: 1.078, 95% CI: 1.014–1.146, P=0.016).
A significant association between Mink S38G gene polymorphism and AF risk was found.
G allele carriers may predispose to AF.
American Psychological Association (APA)
Li, Yan-yan& Wang, Lian-sheng& Lu, Xin-zheng. 2014. Mink S38G Gene Polymorphism and Atrial Fibrillation in the Chinese Population: A Meta-Analysis of 1871 Participants. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1050982
Modern Language Association (MLA)
Li, Yan-yan…[et al.]. Mink S38G Gene Polymorphism and Atrial Fibrillation in the Chinese Population: A Meta-Analysis of 1871 Participants. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1050982
American Medical Association (AMA)
Li, Yan-yan& Wang, Lian-sheng& Lu, Xin-zheng. Mink S38G Gene Polymorphism and Atrial Fibrillation in the Chinese Population: A Meta-Analysis of 1871 Participants. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1050982
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1050982